Others

VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC₅₀ of 290 nM. VU590 also inhibits Kir7.1, with an IC₅₀ of 8 μM. VU590 is not a good probe of ROMK function in the kidney.

DPPC-d₆₂ is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice.

GSK1820795A, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38).

1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin.

Dextran T100 (MW 100,000) (Dextran 100; Dextran D100) is a dehydrated glucose polymer with an average molecular weight of 100,000. Dextran T100 (MW 100,000) has an α-(1→6)-linked D-glucose backbone and α-(1→4)-, α-(1→3)- or α-(1→2)-linked D-glucose side chains, and it is synthesized by lactic acid bacteria or their enzymes. Dextran T100 (MW 100,000) possesses favorable biodegradability and biocompatibility, and it can be used in the fields of food, pharmaceuticals, cosmetics and research.

CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC₅₀ of 640 nM for hCNT2.

O-Phospho-L-threonine is a threonine derivative.

EphB1-IN-1 (Compound 1) is a potent EphB1 inhibitor with IC₅₀s of 3.0, 15 and 220 nM against EphB1^G703C, EphB1^T697G and EphB1^WT, respectively.

Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays.

KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC₅₀ of 0.24 nM in Neuro2A cells.

PTGR2-IN-1 is a potent PTGR2 inhibitor with an IC₅₀ of ~0.7 μM. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.

Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate is used for transdermal delivery of some compounds. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired.

(2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a bicyclic hydrophobic proline analog that acts as a polyproline-II helix stabilizer. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid serves as a structural component of Perindopril (HY-B0130). (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid can be used in studies related to organic synthesis.

2-Acetylthiophene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Boc-His-OMe is a histidine derivative.

4-Bromo-2-fluoropyridine is a drug intermediate.

6-Methoxypyridine-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

3-(Trifluoromethyl)phenylboronic acid usually undergoes linear selective hydroarylation reaction with alkenes as a substrate.

eIF4A3-IN-8 serves as a negative control targeting eukaryotic initiation factor 4A3 (eIF4A3), with an IC₅₀ > 100 μM; it exhibits no significant activity.

Pyrazinamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.