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  3. KT182

KT182 

Cat. No.: HY-120177 Purity: ≥98.0%
Handling Instructions

KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.

For research use only. We do not sell to patients.

KT182 Chemical Structure

KT182 Chemical Structure

CAS No. : 1402612-62-7

Size Price Stock Quantity
5 mg USD 190 In-stock
Estimated Time of Arrival: December 31
10 mg USD 290 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1].

IC50 & Target

IC50: 0.24 nM (ABHD6 in Neuro2A cells)[1].

Molecular Weight

438.52

Formula

C₂₇H₂₆N₄O₂

CAS No.
SMILES

O=C(N1N=NC(C2=CC=C(C3=CC=CC(CO)=C3)C=C2)=C1)N4C(C5=CC=CC=C5)CCCC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (228.04 mM; Need ultrasonic)

Ethanol : 11 mg/mL (25.08 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2804 mL 11.4020 mL 22.8040 mL
5 mM 0.4561 mL 2.2804 mL 4.5608 mL
10 mM 0.2280 mL 1.1402 mL 2.2804 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.70 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.70 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.70 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: ≥99.0%

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Keywords:

KT182KT 182KT-182MAGLMonoacylglycerol lipaseInhibitorinhibitorinhibit

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Product Name:
KT182
Cat. No.:
HY-120177
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