1. GPCR/G Protein
    Neuronal Signaling
  2. Neurokinin Receptor

Serlopitant (Synonyms: VPD-737; MK-0594)

Cat. No.: HY-12114
Handling Instructions

Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.

For research use only. We do not sell to patients.

Serlopitant Chemical Structure

Serlopitant Chemical Structure

CAS No. : 860642-69-9

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.

IC50 & Target

Neurokinin-1 receptor[1]

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8001 mL 9.0004 mL 18.0008 mL
5 mM 0.3600 mL 1.8001 mL 3.6002 mL
10 mM 0.1800 mL 0.9000 mL 1.8001 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

555.53

Formula

C₂₉H₂₈F₇NO₂

CAS No.

860642-69-9

SMILES

O=C1C=C(N2C[[email protected]@]3([H])CC[[email protected]](O[[email protected]@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[[email protected]@H](C5=CC=C(F)C=C5)[[email protected]]3([H])C2)CC1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Serlopitant
Cat. No.:
HY-12114
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Serlopitant

Cat. No.: HY-12114