Siltenzepine
Siltenzepine (AWD 26-06 free base) is an antagonist of mAChR with anti-acid activity, which can be used in peptic ulcers research. Siltenzepine exhibits rapidly but incompletely absorbed characterastic in rats (po).
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- CAS No.: 98374-54-0
- Formule: C19H20ClN3O4
- Masse moléculaire:389.83
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 98374-54-0
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Masse moléculaire 389.83
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Formule C19H20ClN3O4
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SMILES
O=C1C2=CC=CC=C2N(C(CN(CCO)CCO)=O)C3=CC=C(Cl)C=C3N1
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Synonyms
AWD 26-06 free base
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Pfeifer S, et al. Biotransformation und Pharmakokinetik von AWD 26-06, 8-Chlor-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H- dibenzo[d,c][1,4]diazepin-11-on-hydrochlorid an der Ratte [Biotransformation and pharmacokinetics of AWD 26-06, 8-chloro-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H-dibenzo[d, c][1,4]diazepin-11-one hydrochloride in the rat]. Pharmazie. 1990 Jul;45(8):603-7. German. [Content Brief]
[2]. Trausch B, et al. The biliary and renal elimination of the new muscarinic-1-antagonist AWD 26-06 in volunteers with T-tube after cholecystectomy. Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):508-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)