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ADC Payloads Related Products (219)
Related Products (219)
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(4-NH2)-Exatecan-d5
0 ImagesCat. No.: HY-145397SPurity: 98.62%Synonyms: AZ14170132-d5(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan. (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs).
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PY-4Car2
0 ImagesCat. No.: HY-183912CAS No.: 3054643-04-5PY-4Car2 is a Camptothecin (HY-16560) derivative and a topoisomerase I inhibitor. PY-4Car2 functions as a warhead conjugated via a cleavable linker to the bispecific ADC TJ101. PY-4Car2 can be used as an ADC payload for the research of cancers.
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(1R,9S)-Dxd
0 ImagesCat. No.: HY-13631KCAS No.: 2766786-58-5(1R,9S)-Dxd is an isomer of (Dxd) HY-13631D. (1R,9S)-Dxd is an ADC payload that can be used in the synthesis of ADCs (antibody-drug conjugates).
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(5-Cl)-DXd
0 ImagesCat. No.: HY-W1124025CAS No.: 2813268-45-8(5-Cl)-DXd, a derivative of DXd (HY-13631), is a cytotoxic drug that can be used in synthesis of CDH3-targeting antibody-drug conjugates (ADCs).
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Z56
0 ImagesCat. No.: HY-178837CAS No.: 3077480-61-3Z56 is a Ras protein inhibitor. Z56 can be used for the research of cancer, such as pancreatic cancer.
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Camptothecin (Standard)
0 ImagesSynonyms: Campathecin (Standard); (S)-(+)-Camptothecin (Standard); CPT (Standard)Camptothecin (Standard) (Campathecin (Standard)) is the analytical standard of Camptothecin (HY-16560). This product is intended for research and analytical applications. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
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Luisol A
0 ImagesLuisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog.
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PE-E2K
0 ImagesCat. No.: HY-183911CAS No.: 3105822-56-5
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TAM557
0 ImagesCat. No.: HY-160473CAS No.: 1802499-20-2TAM557 is a cytotoxic tubulysin compound that can be used in enzymatic conjugation reactions.
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Gly-7-MAD-MDCPT TFA
0 ImagesCat. No.: HY-132164BGly-7-MAD-MDCPT (Compound 4b) TFA is an anticancer agent. Gly-7-MAD-MDCPT TFA is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM.
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INX-SM-56
0 ImagesINX-SM-56 is a cytotoxin that can be used for the synthesis of anti-VISTA antibody agent conjugate. VISTA: V-region Immunoglobulin-containing Suppressor of T cell Activation.
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(5-Cl)-Exatecan TFA
0 ImagesCat. No.: HY-160806A(5-Cl)-Exatecan TFA is a derivative of Exatecan (HY-13631) and a DNA topoisomerase inhibitor. (5-Cl)-Exatecan TFA serves as the cytotoxic payload component in antibody-drug conjugates (ADC) targeting ROR1-positive cancers. (5-Cl)-Exatecan TFA is applicable for the research of ROR1-positive cancers.
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Auristatin F-d8
0 ImagesCat. No.: HY-15583SPurity: 99.82%Auristatin F-d8 is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .
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DeBoc-Cabazitaxel
0 ImagesCat. No.: HY-W744459CAS No.: 1638286-64-2DeBoc-Cabazitaxel is an ADC linker.
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Taltobulin intermediate-8
0 ImagesTaltobulin intermediate-8 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis.
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Dap-NE
0 ImagesDap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162).
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Auristatin E (GMP)
0 ImagesCat. No.: HY-15582GCAS No.: 160800-57-7Auristatin E (GMP) is Auristatin E (HY-15582) produced by using GMP guidelines. Auristatin E is a tubulin polymerization inhibitor.
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Aldoxorubicin hydrochloride
0 ImagesCat. No.: HY-16261CCAS No.: 1361563-03-2Synonyms: INNO-206 hydrochloride; DOXO-EMCH hydrochlorideAldoxorubicin (INNO-206) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin hydrochloride (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models.
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DGN462
0 ImagesCat. No.: HY-101150CAS No.: 1394079-41-4DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).
