(1R,9S)-Dxd
(1R,9S)-Dxd is an isomer of (Dxd) HY-13631D. (1R,9S)-Dxd is an ADC payload that can be used in the synthesis of ADCs (antibody-drug conjugates).
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- CAS No.: 2766786-58-5
- Formule: C26H24FN3O6
- Masse moléculaire:493.48
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2766786-58-5
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Appearance Solid
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Masse moléculaire 493.48
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Formule C26H24FN3O6
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SMILES
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (202.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (279 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0264 mL | 10.1321 mL | 20.2642 mL | 50.6606 mL |
| 5 mM | 0.4053 mL | 2.0264 mL | 4.0528 mL | 10.1321 mL | |
| 10 mM | 0.2026 mL | 1.0132 mL | 2.0264 mL | 5.0661 mL | |
| 15 mM | 0.1351 mL | 0.6755 mL | 1.3509 mL | 3.3774 mL | |
| 20 mM | 0.1013 mL | 0.5066 mL | 1.0132 mL | 2.5330 mL | |
| 25 mM | 0.0811 mL | 0.4053 mL | 0.8106 mL | 2.0264 mL | |
| 30 mM | 0.0675 mL | 0.3377 mL | 0.6755 mL | 1.6887 mL | |
| 40 mM | 0.0507 mL | 0.2533 mL | 0.5066 mL | 1.2665 mL | |
| 50 mM | 0.0405 mL | 0.2026 mL | 0.4053 mL | 1.0132 mL | |
| 60 mM | 0.0338 mL | 0.1689 mL | 0.3377 mL | 0.8443 mL | |
| 80 mM | 0.0253 mL | 0.1267 mL | 0.2533 mL | 0.6333 mL | |
| 100 mM | 0.0203 mL | 0.1013 mL | 0.2026 mL | 0.5066 mL |
(1R,9S)-Dxd Related Classifications
HY-13631K Related Classifications
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