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Antibodies (14)
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Pseudouridimycin
0 ImagesCat. No.: HY-125650CAS No.: 1566586-52-4Synonyms: PUMPseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC50 of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis. -
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Isopimaric acid
0 ImagesIsopimaric acid is a coniferous tree defense compound. Isopimaric acid binds to AKT and inhibits mTOR phosphorylation, thereby regulating the AKT/mTOR pathway. Isopimaric acid inhibits oxidative stress, inflammation, microglial migration, apoptosis, autophagic flux, ornithine decarboxylase activity, breast cancer proliferation and metastasis, and fungal spore germination. Isopimaric acid also induces M2 microglial polarization, mitochondrial damage, ROS accumulation, starvation-induced colon cancer cell apoptosis, and breast cancer cell cycle arrest. Isopimaric acid activates potassium channels, regulates sodium channels and calcium channels, reduces myocardial excitability, and improves arrhythmia. Isopimaric acid acts as an oxidative substrate for CYP6BW1/3, down-regulates PINK1/Parkin, and regulates calcium homeostasis, oxidative phosphorylation, EMT, and the Wnt pathway. Isopimaric acid exhibits activity against drug-resistant Staphylococcus aureus, repels feeding, and promotes the growth of rice seedlings. Isopimaric acid is suitable for research related to epilepsy, tumors, drug-resistant bacterial infections, atrial fibrillation, hypertension, hyperlipidemia, pulmonary tuberculosis, etc. -
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Lactoferricin B (4-14), bovine TFA
0 ImagesCat. No.: HY-P2323Purity: 99.07%Synonyms: LfcinB (20–30) TFALactoferricin B (4-14), bovine (TFA), a peptide corresponding to residues 4-14 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms. -
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L-Methioninamide hydrochloride
0 ImagesL-Methioninamide hydrochloride, a Methionine analogue, is Methionyl-tRNA synthetase inhibitor. -
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Dicresulene diammonium
0 ImagesCat. No.: HY-105967APurity: 99.48%Dicresulene diammonium is an impurity of Policresulen, an organic acid with hemostatic, antimicrobial and antiviral activities. -
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IMPDH2-IN-2
0 ImagesIMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent. -
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(S)-Lansoprazole
0 ImagesSynonyms: Levolansoprazole(S)-Lansoprazole (Levolansoprazole) is an isoform of Lansoprazole (HY-13662), which is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). -
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Lactic acid potassium
0 ImagesLactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative. -
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Procaine hydrochloride (Standard)
0 ImagesProcaine (hydrochloride) (Standard) is the analytical standard of Procaine (hydrochloride). This product is intended for research and analytical applications. Procaine hydrochloride is a DNA-demethylating agent. Procaine hydrochloride acts through multiple targets and has a slow onset and a short duration of action. -
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Sodium new houttuyfonate
0 ImagesSynonyms: SNHSodium new houttuyfonate (SNH) is a partially reversible NDM-1 inhibitor with an IC50 of 14.2 μM. Sodium new houttuyfonate is an inhibitor against renin and angiotensin I converting enzyme (ACE). Sodium new houttuyfonate can recover the antibacterial activity of Meropenem (HY-13678) against E. coli BL21/pET15b-blaNDM-1. -
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Aucubin (Standard)
0 ImagesAucubin (Standard) is the analytical standard of Aucubin. This product is intended for research and analytical applications. Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects. -
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TBT1
0 ImagesTBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM. -
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Lipopolysaccharides, from S. enterica serotype minnesota Re 595 (Re mutant)
0 ImagesCat. No.: HY-D1056C5Synonyms: LPS, from Salmonella enterica (Serotype minnesota Re 595 (Re mutant))Lipopolysaccharides (LPS), from S. enterica (Salmonella enterica) serotype minnesota Re 595 (Re mutant) is prepared from Salmonella enterica strain Re 595 (Re mutant). The structure in the LPS of strain Re 595 was shown to induce secretion and aggregation in human platelets.
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use. -
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Sulfometuron-methyl
0 ImagesCat. No.: HY-B1852CAS No.: 74222-97-2Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III. -
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Mellein
0 ImagesMellein ((R)-Mellein) is an isocoumarin compound with antibacterial activity. Mellein inhibits the activity of HCV Protease, disrupts the cell wall of Xanthomonas sp., and acts as an insect trail pheromone. Mellein is applicable to research related to fungal infections, bacterial infections, and hepatitis C virus infections. -
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Bixafen
0 ImagesBixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor. -
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Clinafloxacin
0 ImagesSynonyms: AM-1091; CI-960; PD 127391Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro. Clinafloxacin is against DNA gyrase and topoisomerase IV of?S. aureus with IC50 values of 0.92 μg/ml and 1.62 μg/ml, respectively. -
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- Syringic acid (Standard)
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D-Glucose-13C6,d7
0 ImagesSynonyms: Glucose-13C6,d7; D-(+)-Glucose-13C6,d7; Dextrose-13C6,d7D-Glucose-13C6,d7 is the deuterium and 13C labeled D-Glucose. -
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Rifampicin-d4
0 ImagesCat. No.: HY-B0272S2Synonyms: Rifampin-d4; Rifamycin AMP-d4Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. -
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