2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Isopimaric acid

Isopimaric acid is a potent opener of large conductance calcium activated K+ (BK) channels.

For research use only. We do not sell to patients.

Isopimaric acid Chemical Structure

Isopimaric acid Chemical Structure

CAS No. : 5835-26-7

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10 mg USD 870 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Isopimaric acid is a potent opener of large conductance calcium activated K+ (BK) channels.

Molecular Weight

302.45

Formula

C20H30O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC=C3[C@]2([H])CC[C@@](C=C)(C)C3)([H])[C@@](C)(CCC1)C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 25 mg/mL (82.66 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3063 mL 16.5317 mL 33.0633 mL
5 mM 0.6613 mL 3.3063 mL 6.6127 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (310 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3063 mL 16.5317 mL 33.0633 mL 82.6583 mL
5 mM 0.6613 mL 3.3063 mL 6.6127 mL 16.5317 mL
10 mM 0.3306 mL 1.6532 mL 3.3063 mL 8.2658 mL
15 mM 0.2204 mL 1.1021 mL 2.2042 mL 5.5106 mL
20 mM 0.1653 mL 0.8266 mL 1.6532 mL 4.1329 mL
25 mM 0.1323 mL 0.6613 mL 1.3225 mL 3.3063 mL
30 mM 0.1102 mL 0.5511 mL 1.1021 mL 2.7553 mL
40 mM 0.0827 mL 0.4133 mL 0.8266 mL 2.0665 mL
50 mM 0.0661 mL 0.3306 mL 0.6613 mL 1.6532 mL
60 mM 0.0551 mL 0.2755 mL 0.5511 mL 1.3776 mL
80 mM 0.0413 mL 0.2066 mL 0.4133 mL 1.0332 mL
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Isopimaric acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isopimaric acid5835-26-7Potassium ChannelKcsAInhibitorinhibitorinhibit

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