1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK6 Isoform
  5. CDK6 Ligand

CDK6 Ligand

CDK6 Ligand (1):

Cat. No. Product Name Effect Purity
  • HY-168440
    Aurora-A ligand 1
    Ligand 98.75%
    Aurora-A ligand 1 is a high-affinity and specific Aurora-A inhibitor with a dissociation constant (Kd) value of 0.85 nM. Aurora-A ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC Aurora-A degraders with antitumor activity. Aurora-A ligand 1 can be used for the synthesis of HLB-0532259 (HY-168439). HLB-0532259 shows anti-tumor activity against neuroblastoma.