Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (4062)
Related Products (4062)
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3-Ethoxybenzoic acid
0 ImagesCat. No.: HY-W048341CAS No.: 621-51-23-Ethoxybenzoic acid is a derivative of benzoic acid and serves as both a raw material and an intermediate in organic synthesis.
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3,4'-Dihydroxypropiophenone
0 ImagesCat. No.: HY-W268155CAS No.: 53170-93-73,4'-Dihydroxypropiophenone is a phenylpropanoid that can be isolated from the leaves of the B. platyphylla vat. latifolia and exhibits anti-aging activity.
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3(R)-Hydroxyhexadecanoic acid
0 Images3(R)-Hydroxyhexadecanoic acid is an ester product.
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16-Methyloctadecanoic acid
0 Images16-Methyloctadecanoic acid is an ester product.
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Permethrinic acid methyl ester
0 ImagesCat. No.: HY-W154397CAS No.: 61898-95-1Permethrinic Acid Methyl Ester is a derivative of the insecticide Permethrin (HY-B0887). Permethrin is an insecticide, an acaricide, and a highly selective inhibitor of mitochondrial complex I.
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Fanetizole
0 ImagesFanetizole is an anti-inflammatory agent. Fanetizole can be used for inflammatory diseases research.
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4-epi-Edoxaban tosylate
0 ImagesCat. No.: HY-W062274ACAS No.: 2852734-47-3Synonyms: 4-epi-DU-176b
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Sovaprevir
0 ImagesSynonyms: ACH 0141625Sovaprevir is an active compound.
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WAY-215718
0 ImagesWAY-215718 is an active molecule.
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Indanazoline
0 ImagesCat. No.: HY-U00075CAS No.: 40507-78-6Indanazoline (as monohydrochloride active substance of Farial) is characterized by a pronounced vasoconstrictive action.
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Atrimustine
0 ImagesSynonyms: Bestrabucil; KM2210Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.
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Menbutone
0 ImagesMenbutone (Genabilic acid), an oxobutyric acid derivative, is a choleretic. Menbutone can be used to treat digestive upsets (loss of appetite, indigestion, toxemia, or hepatic and pancreatic insufficiencies) in a variety of animal species, including different farm animals (cattle, sheep, goats, pigs), as well as in dogs.
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3'-Fluorothymidine-5'-triphosphate tetrasodium
0 ImagesSynonyms: 3'-FdTTP tetrasodium3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP (HY-138615) analog. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits the T4 DNA polymerases competitively with dTTP. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits DNA synthesis by T4 wild-type, L98 and CB121 DNA polymerase.
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2-Amino-1-(3-chlorophenyl)-1-propanone hydrochloride
0 Images2-Amino-1-(3-chlorophenyl)-1-propanone hydrochloride is a drug derivative.
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β-D-galactose
0 ImagesCat. No.: HY-W415856CAS No.: 7296-64-2Synonyms: Beta-D-galactoseβ-D-galactose (Beta-D-galactose) is one of the two anomers of D-Galactose (HY-N0210). β-D-galactose efficiently binds to and inhibits the galactose repressor (GalR), thereby inducing the expression of the gal regulon. β-D-galactose acts as a persistent induction signal to trigger the synthesis of UDP-galactose for the biosynthetic glycosylation pathway, rather than serving as a carbon source in Yersinia pestis with inactivated GalM.
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14-Deoxy-17-hydroxyandrographolide
0 ImagesCat. No.: HY-N1488CAS No.: 869384-82-7Synonyms: 14-Deoxy-17β-hydroxyandrographolide14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate.
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1-Palmitoyl-2-oleoyl-3-bromopropanediol
0 Images1-Palmitoyl-2-oleoyl-3-bromopropanediol is an ester product.
