Fluorescent Dye

Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm).
Solvent and concentration: DMSO: 10 mM

JOE phosphoramidite, 5-isomer is a derivative of JOE (dimethoxy-dichloro-carboxyfluorescein) containing a phosphoramidite moiety, used for oligonucleotide synthesis. JOE phosphoramidite, 5-isomer is primarily used in the synthesis of fluorescent oligonucleotide probes (Ex/Em = 520/548 nm).

Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35).

ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.

Cy3 labled SPC4061 sodium is a Cy3 labled SPC4061 sodium.

BG-PEG11-Cya-NR is a high-performance, non washable, fluorescent opening probe. BG-PEG11-Cya-NR has very weak fluorescence in polar environments (such as aqueous solutions), while its fluorescence is significantly enhanced in non-polar environments (such as the lipid bilayer of cell membranes).

RDDB is a rhodamine-based turn-on fluorescent and colorimetric chemosensor selective for Mn²⁺, with a limit of detection of 5×10^-8 M (excitation wavelength: 480-550 nm; fluorescence signal collection range: >590 nm). In the presence of Mn²⁺, RDDB undergoes a spirolactam ring-opening reaction of its rhodamine hydrazide moiety, resulting in turn-on fluorescence and a color change. RDDB can be used for intracellular Mn²⁺ imaging.

FD-1080 Maleimide (FD-1080-MAL) is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging.

D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates.

Prostaglandin D2-biotin is a fluorescent probe that can be used for detecting PGD2.

MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research.

RB-PEG10000-FA (Rhodamine B-PEG10000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG10000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm).

RB-PEG3400-SH (Rhodamine B-PEG3400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm).

CMTDP is a Fluorescent probe for detecting local polarity changes around the Cys34 domain of bovine serum albumin during pH-induced N→B conformational transition. It is a thiol-specific and polarity-sensitive probe; it covalently labels the free cysteine residue at position 34 (Cys34) of bovine serum albumin, and its fluorescence maximum emission wavelength shifts in response to solvent polarity, but not to pH and temperature. When labeled to BSA, as the local polarity around the Cys34 domain increases with rising pH, the probe shows a bathchromic shift in fluorescence emission wavelength and a decrease in fluorescence intensity, which allows quantification of the local polarity change via the relationship between emission wavelength shift and dielectric constant. CMTDP itself has absorption peaks at ~392 and 508 nm, and CMTDP-labeled BSA has excitation maxima at 376 and 470 nm at pH 6.0, with the shorter-wavelength excitation peak red-shifting as pH increases while the longer one remains stable; when excited at 470 nm, the fluorescence emission maximum shifts from 570 nm at pH 6.0 to 577 nm at pH 9.1, while free CMTDP at pH 7.4 has an emission maximum at 621 nm. The excitation/emission wavelengths for CMTDP-labeled BSA are Ex/Em = 376/570 nm at pH 6.0, Ex/Em = ~376+/573 nm at pH 7.4, Ex/Em = ~376+/575 nm at pH 8.0, Ex/Em = ~376+/577 nm at pH 9.1, and for free CMTDP at pH 7.4, Ex/Em (when excited at 470 nm) = 470/621 nm[1].

Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus.

Cellulose Staining Solution (Zinc Chloride-Iodine Method) is a cellulose-targeted staining agent. Cellulose Staining Solution (Zinc Chloride-Iodine Method) enables cellulose cell walls to turn blue-purple to blue by forming iodine-cellulose complexes between iodine and cellulose. Cellulose Staining Solution (Zinc Chloride-Iodine Method) can be used for the identification of plant phloem fibers, cellulose layers of algal cell walls, residual mineralized plant fibers from archaeological samples, and cellulose deposited on PET surfaces.

6-Carboxy-H2DCFDA (6-Carboxy-2',7'-dichlorodihydrofluorescein) is a non-fluorescent, cell-permeable intracellular ROS indicator. 6-Carboxy-H2DCFDA undergoes oxidation to highly fluorescent carboxy-dichlorofluorescein (Ex/Em = 488/520 nm).

Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm).

AF 660 NHS ester is a fluorescent dye AF 660 derivative exhibits high fluorescence quantum yield and high photostability. AF 660 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 668/698 nm).

800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins.