GlyT
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GlyT Related Products (31)
Related Products (31)
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LY2365109 hydrochloride (Standard)
0 ImagesCat. No.: HY-100416ARCAS No.: 1779796-27-8LY2365109 (hydrochloride) (Standard) is the analytical standard of LY2365109 (hydrochloride) (HY-100416A). This product is intended for research and analytical applications. LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
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Stearoyl-L-carnitine-d9 chloride
0 ImagesCat. No.: HY-113202S1CAS No.: 2936622-19-2Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride, a fatty ester lipid molecule, is an endogenous metabolite. Stearoyl-L-carnitine chloride can be used as PKC inhibitor. Stearoyl-L-carnitine chloride accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoyl-L-carnitine chloride inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoyl-L-carnitine chloride acts as a metabolomics biomarker for Parkinson’s disease. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2.
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Bitopertin (Standard)
0 ImagesSynonyms: RG1678 (Standard); RO4917838 (Standard)Bitopertin (Standard) is the analytical standard of Bitopertin. This product is intended for research and analytical applications. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
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SSR504734 (Standard)
0 ImagesCat. No.: HY-10715RCAS No.: 615571-23-8SSR504734 (Standard) is the analytical standard of SSR504734 (HY-10715). This product is intended for research and analytical applications. SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities.
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Org 25543 hydrochloride (Standard)
0 ImagesCat. No.: HY-107527RCAS No.: 495076-64-7Org 25543 hydrochloride (Standard) is the analytical standard of Org 25543 (hydrochloride) (HY-107527). This product is intended for research and analytical applications. Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor (IC50: 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice.
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Opiranserin hydrochloride (Standard)
0 ImagesCat. No.: HY-109067ARCAS No.: 1440796-75-7Synonyms: VVZ-149 hydrochloride (Standard)Opiranserin hydrochloride (Standard) is the analytical standard of Opiranserin (hydrochloride) (HY-109067A). This product is intended for research and analytical applications. Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain.
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Stearoyl-L-carnitine-d3
0 ImagesCat. No.: HY-113202SCAS No.: 1021439-31-5Stearoyl-L-carnitine-d3 is the deuterium labeled Stearoylcarnitine. Stearoylcarnitine, a fatty ester lipid molecule, is an endogenous metabolite. Stearoylcarnitine can be used as PKC inhibitor. Stearoylcarnitine accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoylcarnitine inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoylcarnitine acts as a metabolomics biomarker for Parkinson’s disease. Stearoylcarnitine is a less potent inhibitor of GlyT2.
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ASP2535 (Standard)
0 ImagesCat. No.: HY-110176RCAS No.: 374886-51-8ASP2535 (Standard) is the analytical standard of ASP2535 (HY-110176). This product is intended for research and analytical applications. ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor. ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer's disease.
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Stearoyl-L-carnitine chloride (Standard)
0 ImagesStearoyl-L-carnitine (chloride) (Standard) is the analytical standard of Stearoyl-L-carnitine (chloride). This product is intended for research and analytical applications. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.
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PF-03463275 (Standard)
0 ImagesCat. No.: HY-10716ARCAS No.: 1173239-39-8PF-03463275 (Standard) is the analytical standard of PF-03463275 (HY-10716A). This product is intended for research and analytical applications. PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 has the potential for Schizophrenia research.
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MPDC hydrochloride
0 ImagesCat. No.: HY-101334AMPDC hydrochloride is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes.
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