Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2548)
Related Products (2548)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Antiparasitic agent-46
0 ImagesCat. No.: HY-184085CAS No.: 100967-19-9Antiparasitic agent-46 is a p-aminophenoxypropyl-based monoamine and a structural analog of Antiparasitic agent-45 (HY-184084). Antiparasitic agent-46 shows no activity against Schistosoma mansoni in mice and exhibits extremely strong acute oral toxicity. Antiparasitic agent-46 can be used in studies related to schistosome infection.
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DHFR-IN-20
0 ImagesCat. No.: HY-168069DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme.
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Cyetpyrafen
0 ImagesCat. No.: HY-W727481CAS No.: 1253429-01-4Cyetpyrafen is a pyrazole insecticide/acaricide with broad-spectrum insecticidal activity. Cyetpyrafen binds to DhelOBP4 (Ki = 4.95 μM) and DhelOBP21 (Ki = 5.51 μM) to mediate olfactory recognition in *Cryptolaemus montrouzieri*. Cyetpyrafen induces dose-dependent electroantennogram responses in *Cryptolaemus montrouzieri* and exhibits repellent effects on the species. Cyetpyrafen has bioaccumulative properties, is rapidly and passively absorbed by the roots of lettuce and rice, reaches a steady state within 24 h, preferentially accumulates in roots, and shows limited xylem/phloem translocation.
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Cytosaminomycin B
0 ImagesCat. No.: HY-N14068CAS No.: 157878-03-0Cytosaminomycin B has anti-Eimeria Tenella activity.
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Pheanthine
0 ImagesPheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM).
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CYP3A4-IN-5
0 ImagesCat. No.: HY-175345CAS No.: 70619-09-9CYP3A4-IN-5 (Compound 5p) is a potent Leishmania major pteridine reductase 1 (Lm PTR1) inhibitor (IC50=12.77 µM). CYP3A4-IN-5 is promising for research of parasite infection.
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BRD7929
0 ImagesCat. No.: HY-187550CAS No.: 1771650-41-9BRD7929 is an orally active phenylalanyl-tRNA synthetase (PheRS) inhibitor and parasiticide, with an IC50 value of 0.023 μM against Plasmodium falciparum PheRS. BRD7929 inhibits the aminoacylation activity of the target enzyme, blocking protein synthesis, DNA replication and parasite nuclear division. BRD7929 clears the asexual blood stage, liver stage and mature gametocyte stage of malaria parasite species, and prevents parasite transmission to mosquitoes. BRD7929 shows moderate cytotoxicity against mammalian cells and inhibits hERG ion channels. BRD7929 achieves cure of malaria in animal models. BRD7929 can be used in research related to cryptosporidiosis and malaria.
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G-418 (Standard)
0 ImagesCat. No.: HY-108718RCAS No.: 49863-47-0Synonyms: Geneticin (Standard); Antibiotic G-418 (Standard)G-418 (Standard) is the analytical standard of G-418 (HY-108718). This product is intended for research and analytical applications. G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis.
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Cytosaminomycin C
0 ImagesCat. No.: HY-N14069CAS No.: 157878-04-1Cytosaminomycin C has anti-Eimeria Tenella activity.
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K11002 hydrobromide
0 ImagesCat. No.: HY-183387CAS No.: 1348565-08-1K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness).
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Antileishmanial agent-34
0 ImagesCat. No.: HY-W631668CAS No.: 139276-16-7Antileishmanial agent-34 (Fig. (9), compound 3) is an aurone with antileishmanial activity. Antileishmanial agent-34 against extracellular forms of Lmaj, Ldon, Linf and Lenr as well as against intracellular forms of Ldon (IC50 of <2 µg/mL).
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Quinine hydrochloride dihydrate (Standard)
0 ImagesCat. No.: HY-B0433ARCAS No.: 6119-47-7Quinine (hydrochloride dihydrate) (Standard) is the analytical standard of Quinine (hydrochloride dihydrate). This product is intended for research and analytical applications. Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
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Stibophen
0 ImagesCat. No.: HY-180388CAS No.: 15489-16-4Stibophen is a potent antiparasitic agent is effective against Litomosoides carinii, Dipetalonema witei, and Brugia pahangi. Stibophen inhibits lactate accumulation and phosphofructokinases (PFK) activity in adult filariids. Stibophen also inhibits Ascaris and Hymenolepis diminuta PFK without inhibiting mammalian liver PFK. Stibophen can be used for the research of schistosomiasis and filariid infections.
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3-ANOT (Standard)
0 ImagesCat. No.: HY-136458RCAS No.: 3572-44-9Synonyms: 3-Amino-5-nitro-o-toluamide (Standard)3-ANOT (Standard) is the analytical standard of 3-ANOT. This product is intended for research and analytical applications. 3-ANOT is a metabolite of Dinitolmide (a nitroamide coccidiostat commonly used in poultry production).
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Uredofos
0 ImagesCat. No.: HY-123192CAS No.: 52406-01-6Synonyms: SansalidUredofos is a broad-spectrum anthelmintic. Uredofos has anticestodal activity.
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Ipronidazole (Standard)
0 ImagesCat. No.: HY-151217RCAS No.: 14885-29-1Synonyms: RO-71554 (Standard)Ipronidazole (Standard) is the analytical standard of Ipronidazole. This product is intended for research and analytical applications. Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water.
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DSM267
0 ImagesCat. No.: HY-117908CAS No.: 1281861-06-0DSM267 is a triazolopyrimidine inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), with an IC50 of 38 nM, while its IC50 against human DHODH exceeds 100000 nM. DSM267 is used for the in vitro systematic screening and characterization of the resistance evolution pathways of Plasmodium falciparum to DHODH inhibitors.
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(rac)-Monepantel
0 ImagesSynonyms: (rac)-AAD1566; (rac)-NUZ-001(rac)-Monepantel ((rac)-AAD1566) is the racemic form of Monepantel (HY-14774). Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor.
