Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2567)
Related Products (2567)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
Antiparasitic agent-42
0 ImagesCat. No.: HY-W035445CAS No.: 102010-61-7Antiparasitic agent-42 is an orally active p-aminophenoxyalkane derivative with anti-Schistosoma mansoni activity. Antiparasitic agent-42 exerts retinal toxicity in cats. Antiparasitic agent-42 can be used in the research of schistosomiasis.
-
Domiphen bromide (Standard)
0 ImagesDomiphen bromide (Standard) is the analytical standard of Domiphen bromide (HY-B1467). This product is intended for research and analytical applications. Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
-
HDAC1-IN-12
0 ImagesCat. No.: HY-181010HDAC1-IN-12 is a Plasmodium falciparum HDAC1 (PfHDAC1) inhibitor with an IC50 of 4.1 nM against Pf3D7. HDAC1-IN-12 inhibits PfHDAC1, upregulates histone H3 acetylation in P. falciparum parasites, downregulates malaria invasion-related gene expression, and exhibits favorable safety profiles, improved physicochemical properties, and potent in vivo antimalarial activity. HDAC1-IN-12 can be used for the research of malaria.
-
Arohynapene B
0 ImagesCat. No.: HY-W714863CAS No.: 154445-09-7Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria tenella.
-
Clindamycin B
0 ImagesCat. No.: HY-W777995CAS No.: 18323-43-8
-
Butonate
0 ImagesButonate is an insecticide. Butonate is an orally active anthelmintic.
-
Avermectin B1a aglycon
0 ImagesCat. No.: HY-137968CAS No.: 71828-14-3Avermectin B1a aglycon is an aglycone derivative of Avermectin B1a (HY-15308), an antiparasitic agent that paralyzes nematodes. Avermectin B1a aglycon hyperpolarizes P. crassipes muscle fibers, with a minimum effective concentration of 0.1 μM.
-
Melicopine
0 ImagesCat. No.: HY-W437569CAS No.: 568-01-4Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC50 greater than 100 µg/mL). Melicopine holds promise for research in anticancer and anti-infection fields.
-
Quinine dihydrochloride
0 ImagesQuinine dihydrochloride is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
-
Chloroxine (Standard)
0 ImagesChloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp.
-
WEHI-326
0 ImagesCat. No.: HY-175362WEHI-326 is a potent antimalarial agent targeting Plasmodium falciparum ROM8 and CSC1 proteins (IC50=0.006 μM). WEHI-326 is promising for research of malaria.
-
AB 3217-A
0 ImagesCat. No.: HY-117986CAS No.: 139158-99-9Synonyms: Antibiotic AB3217AAB 3217-A, an anti-mite substance, can be isolated from the fermentation broth of a streptomycete strain.
-
PfSUB1-IN-2
0 ImagesCat. No.: HY-187525PfSUB1-IN-2 is an irreversible covalent peptidic diaryl phosphonate inhibitor of Plasmodium falciparum serine protease PfSUB1 with an IC50 of 167 nM and an EC50 of 22.2 μM against Plasmodium falciparum strain growth. PfSUB1-IN-2 can be used for the research of malaria.
-
TDR 32750
0 ImagesCat. No.: HY-119707CAS No.: 1428183-45-2TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM.
-
PI4Kβ/PKG-IN-1
0 ImagesCat. No.: HY-174130PI4Kβ/PKG-IN-1 (Compound 19) is an orally active dual inhibitor targeting Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-1 exhibits potent antiplasmodial activity. PI4Kβ/PKG-IN-1 is promising for research of malaria.
-
Teroxalene
0 ImagesCat. No.: HY-183178CAS No.: 14728-33-7Teroxalene is a piperazine-based Schistosomicide. Teroxalene is used for the research of schistosomiasis.
-
Hycanthone (Standard)
0 ImagesHycanthone (Standard) is the analytical standard of Hycanthone (HY-B1099). This product is intended for research and analytical applications. Hycanthone is an apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor, DNA intercalator and Antischistosomal agent, with an IC50 of 80 nM against APE1. Hycanthone irreversibly inhibits thymidine incorporation into DNA in adult sensitive *Schistosoma mansoni*, while exerts weak inhibitory effects on uridine and leucine incorporation. Hycanthone reduces influenza virus-induced interferon production. Hycanthone exhibits mutagenic effects in various organisms, shows teratogenicity in mice and rabbits, and induces neoplastic liver lesions in partially hepatectomized mice. Hycanthone can be used in research related to schistosomiasis and cancer.
-
DHFR-IN-28
0 ImagesCat. No.: HY-W167448CAS No.: 1931-17-5DHFR-IN-28 is an inhibitor of Plasmodium falciparum dihydrofolate reductase (DHFR), with a Ki value of 20.0 nM against wild-type pfDHFR. DHFR-IN-28 inhibits the growth of both wild-type and A16V+S108T mutant Plasmodium falciparum. DHFR-IN-28 is applicable for research related to malaria.
-
5-Phenylthieno[2,3-d]pyrimidin-4-amine
![5-Phenylthieno[2,3-d]pyrimidin-4-amine](https://file.medchemexpress.com/product_pic/hy-w079315.gif "Click to View 5-Phenylthieno[2,3-d]pyrimidin-4-amine Product Detail")
0 ImagesCat. No.: HY-W079315CAS No.: 195193-10-35-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities.
