RSV
Respiratory syncytial virus
RSV (Respiratory syncytial virus) is a leading cause of acute respiratory infections. RSV can exploit host immunity and cause a strong inflammatory response that leads to lung damage and virus dissemination. There is a single RSV serotype with two major antigenic subgroups, A and B.
RSV is a non-segmented negative-sense single-stranded enveloped RNA virus that belongs to the family of Paramyxoviridae, genus Pneumovirus, subfamily Pneumovirinae. Its 10 genes encode 11 proteins since two overlapping open reading frames in the M2 mRNA yield two distinct matrix proteins, M2-1 and M2-2. The viral envelope contains three proteins, the G glycoprotein, the fusion (F) glycoprotein, and the small hydrophobic (SH) protein. The RSV virus comprises five other structural proteins, the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1, and two non-structural proteins (NS1 and NS2).
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RSV Related Products (144)
Related Products (144)
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Recombinant Proteins (11)
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Antibodies (1)
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JNJ-7184
0 ImagesCat. No.: HY-161771CAS No.: 2347368-51-6
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Ac-CoA Synthase-IN-1 (Standard)
0 ImagesCat. No.: HY-104032RCAS No.: 508186-14-9Ac-CoA Synthase-IN-1 (Standard) is the analytical standard of Ac-CoA Synthase-IN-1 (HY-104032). This product is intended for research and analytical applications. Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM. Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV).
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Asvasiran sodium scrambled negative control
0 ImagesCat. No.: HY-158824BAsvasiran sodium scrambled negative control is the sequence scrambled negative control of Asvasiran sodium.
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Lonafarnib (Standard)
0 ImagesSynonyms: Sch66336 (Standard)Lonafarnib (Standard) (Sch66336 (Standard)) is the analytical standard of Lonafarnib (HY-15136). This product is intended for research and analytical applications. Lonafarnib (Sch66336) is an orally active, blood-brain barrier penetrant farnesyltransferase (FPTase) inhibitor. Lonafarnib increases the phosphorylation levels of Akt, CaMKII and CREB, upregulates BDNF expression in the hippocampus, elevates the content of α7nAChR on cell membranes, and blocks the isoprenylation of H-Ras. Lonafarnib repairs synapses and reverses spatial memory deficits in Aβ1-42 model mice. Lonafarnib inhibits RSV fusion and replication, and alleviates virus-induced lung injury. Lonafarnib activates the lysosomal and autophagic pathways, and reduces the phosphorylation and aggregation of tau. Lonafarnib acts synergistically with Sorafenib (HY-10201) to promote apoptosis, and inhibits the proliferation and invasion of melanoma cells. Lonafarnib inhibits the farnesylation of progerin, repairs nuclear membrane defects, and activates the cGAS-STING-STAT1 signaling pathway. Lonafarnib can be used in research related to diseases including Alzheimer's disease, viral infections, melanoma, and progeria.
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Asvasiran
0 ImagesCat. No.: HY-158824CAS No.: 870094-26-1Synonyms: ALN-RSV01Asvasiran is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.
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Ziresovir (Standard)
0 ImagesCat. No.: HY-109142RCAS No.: 1422500-60-4Synonyms: AK0529 (Standard); RO-0529 (Standard)Ziresovir (Standard) is the analytical standard of Ziresovir (HY-109142). This product is intended for research and analytical applications. Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacoKinetics in animal species.
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AZD4316
0 ImagesCat. No.: HY-120660CAS No.: 1243324-08-4AZD-4316 is a respiratory syncytial virus (RSV) L protein inhibitor. AZD-4316 has an inhibitory effect on RSV A subtypes (such as strain A2) and can effectively block viral replication in the early stage of infection (the viral entry stage). AZD-4316 is inactive when administered 12-24 hours after infection. AZD-4316 can be used for the research of RSV infection.
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Enzaplatovir (Standard)
0 ImagesCat. No.: HY-109004RCAS No.: 1323077-89-9Synonyms: BTA-C585 (Standard)Enzaplatovir (Standard) is the analytical standard of Enzaplatovir (HY-109004). This product is intended for research and analytical applications. Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection.
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RSV-IN-13
0 ImagesCat. No.: HY-171983CAS No.: 2724259-07-6
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Alizarin complexone (Standard)
0 ImagesCat. No.: HY-121075RCAS No.: 3952-78-1Alizarin complexone (Standard) is the analytical standard of Alizarin complexone (HY-121075). This product is intended for research and analytical applications. Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens.
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Rostafuroxin (Standard)
0 ImagesCat. No.: HY-12283RCAS No.: 156722-18-8Synonyms: PST 2238 (Standard)Rostafuroxin (Standard) is the analytical standard of Rostafuroxin. This product is intended for research and analytical applications. Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity.
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A 33903
0 ImagesCat. No.: HY-108002CAS No.: 70890-53-8A 33903 is a respiratory syncytial virus (RSV) replication inhibitor. A 33903 can be used for the research of RSV-infection.
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PC786 (Standard)
0 ImagesCat. No.: HY-102038RCAS No.: 1902114-15-1PC786 (Standard) is the analytical standard of PC786 (HY-102038). This product is intended for research and analytical applications. PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM).
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Perflubron (Standard)
0 ImagesSynonyms: Perfluorooctyl bromide (Standard); 1-Bromoperfluorooctane (Standard); PFOB (Standard)Perflubron (Standard) is the analytical standard of Perflubron. This product is intended for research and analytical applications. Perflubron (Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Perflubron can be emulsified with egg phospholipids (EYP) and shows exceptionally fast excretion characteristics.
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ASN-500
0 ImagesCat. No.: HY-P991497ASN-500 is a human monoclonal antibody (mAb) targeting F/Fusion glycoprotein F0. ASN-500 can be used in respiratory syncytial virus infection research.
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4,5-O-Dicaffeoyl quinic acid methyl ester
0 ImagesCat. No.: HY-N12305CAS No.: 188742-80-5
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(S)-Enzaplatovir (Standard)
0 ImagesCat. No.: HY-109004ARCAS No.: 1323077-88-8Synonyms: (S)-BTA-C585 (Standard)(S)-Enzaplatovir (Standard) is the analytical standard of (S)-Enzaplatovir (HY-109004A). This product is intended for research and analytical applications. (S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV) (patent WO2011094823A1 compound 77).
