1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14732
    Demycarosyl platenomycin
    Demycarosylplatenomycin (DM-PLM) is an antibiotic with weak activity against Gram-positive bacteria.
    Demycarosyl platenomycin
  • HY-N14977
    Epoxyquinomicin C
    Epoxyquinomicin C is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin C exhibits anti-inflammatory effects against collagen-induced arthritis. Epoxyquinomicin C can be designed for synthesis of the NF-κB Inhibitor DHMEQ.
    Epoxyquinomicin C
  • HY-N14468
    Pneumocandin B2
    Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL.
    Pneumocandin B2
  • HY-13588R
    Cefsulodin sodium (Standard)
    Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM.
    Cefsulodin sodium (Standard)
  • HY-126954
    13-Deoxycarminomycin
    13-Deoxycarminomycin is an antibiotic with antibacterial activity. 13-Deoxycarminomycin also exhibits cytotoxicity against tumor cells such as HeLa and P388, and can play an anti-tumor role.
    13-Deoxycarminomycin
  • HY-N14012
    Cedarmycin B
    Cedarmycin B has activities against Candida, Cryptococcus neoforme and Aspergillus fumigatus, with the MIC values of 12.5-50 μg/mL.
    Cedarmycin B
  • HY-B1336R
    Furazolidone (Standard)
    Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM.
    Furazolidone (Standard)
  • HY-B0220S
    Erythromycin-d6
    Erythromycin-d6 is the deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid.
    Erythromycin-d<sub>6</sub>
  • HY-N12498
    Aureonuclemycin
    Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. .
    Aureonuclemycin
  • HY-N15076
    Herbimycin B
    Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells.
    Herbimycin B
  • HY-N14504
    Mycinamicin V
    Monamycin V is an ester peptide antibiotic. Monamycin V has activity against Gram-positive bacteria.
    Mycinamicin V
  • HY-129316
    (S)-Dihydroaeruginoic acid
    (S)-Dihydroaeruginoic acid is an antibiotic originally isolated from P. fluorescens. It has antimicrobial activity in a disc assay against R. solani, P. ultimum, B. cinera, S. rolfsii, C. gloeosporioide, F. oxysporum, and S. tritici fungi as well as B. subtilis, E. herbicola, and S. albus bacteria when used at a concentration of 200 μg/disc.
    (S)-Dihydroaeruginoic acid
  • HY-N14856
    Verlamelin
    Verlamelin is a depsipeptide antibiotic. Verlamelin has anti-fungal activity against plant pathogens.
    Verlamelin
  • HY-W715444
    Mucidin
    Mucidin is an antifungal antibiotic that inhibits electron-transfer reactions in the cytochrome bc1 complex of the mitochondrial respiratory chain.
    Mucidin
  • HY-102008
    LBM-415
    LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy.
    LBM-415
  • HY-B0957R
    Erythromycin Ethylsuccinate (Standard)
    Erythromycin Ethylsuccinate (Standard) is the analytical standard of Erythromycin Ethylsuccinate. This product is intended for research and analytical applications. Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.
    Erythromycin Ethylsuccinate (Standard)
  • HY-N14412
    Napyradiomycin A2
    Napyradiomycin A2 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity.
    Napyradiomycin A2
  • HY-101938R
    Sinefungin (Standard)
    Sinefungin (Standard) is the analytical standard of Sinefungin (HY-101938). This product is intended for research and analytical applications. Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.
    Sinefungin (Standard)
  • HY-182622
    Etimicin
    Etimicin is a fourth-generation semisynthetic aminoglycoside antibiotic. Etimicin exhibits broad spectrum of activity against gram-positive, gram-negative, and aminoglycoside-resistant bacterial strains, with lower ototoxicity and nephrotoxicity. Etimicin exerts rapid, concentration-dependent bactericidal activity against bacteria. Etimicin can be used for the research of bacterial infections.
    Etimicin
  • HY-B1085R
    Cinoxacin (Standard)
    Cinoxacin (Standard) is the analytical standard of Cinoxacin. This product is intended for research and analytical applications. Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.
    Cinoxacin (Standard)

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