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Beta-lactamase Related Products (198)
Related Products (198)
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Cefonicid sodium
0 ImagesCat. No.: HY-B1300CAS No.: 61270-78-8Cefonicid sodium is a long-acting cephalosporin antibiotic. Cefonicid sodium also acts as a noncompetitive class I β-lactamase inhibitor with a Ki value of 0.8 μM. Cefonicid sodium exhibits broad-spectrum antimicrobial activity and is effective against a variety of Gram-positive and Gram-negative bacteria. Cefonicid sodium can be used for research on infections.
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Eravacycline-d4 dihydrochloride
0 ImagesCat. No.: HY-16980SSynonyms: TP-434-d4 dihydrochlorideEravacycline-d4 (TP-434-d4) dihydrochloride is deuterium labeled Eravacycline. Eravacycline is a potent and broad-spectrum antibacterial agent.
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Avibactam sodium (Standard)
0 ImagesSynonyms: NXL-104 (Standard)Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
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Funobactam
0 ImagesSynonyms: XNW4107Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria.
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Ceftazidime (Standard)
0 ImagesSynonyms: GR20263 (Standard)Ceftazidime (Standard) is the analytical standard of Ceftazidime. This product is intended for research and analytical applications. Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.
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3′,4′,7-Trihydroxyflavone
0 Images3′,4′,7-Trihydroxyflavone is an orally active inhibitor of OXA-48 (IC50 = 1.89 μM) and COX-1 (IC50 = 36.37 μM). 3′,4′,7-Trihydroxyflavone exhibits antioxidant and anti-inflammatory properties, inhibiting the release of inflammatory cytokines such as IL-6, IL-8, and TNF-α. 3′,4′,7-Trihydroxyflavone inhibits H2O2-induced neuronal apoptosis and ROS accumulation, and exerts anti-neuroinflammatory effects by suppressing the JNK-STAT1 pathway. 3′,4′,7-Trihydroxyflavone exhibits antimicrobial and antibiotic-modifying activities against multidrug-resistant Gram-negative enteric bacteria. 3′,4′,7-Trihydroxyflavone inhibits RANKL-induced osteoclast formation via NFATc1. 3′,4′,7-Trihydroxyflavone activates the CREB-BDNF axis and restores scopolamine (HY-N0296)-induced memory deficits in mice.
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Ceftazidime pentahydrate (Standard)
0 ImagesSynonyms: GR20263 pentahydrate (Standard)Ceftazidime (pentahydrate) (Standard) is the analytical standard of Ceftazidime (pentahydrate). This product is intended for research and analytical applications. Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.
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CENTA
0 ImagesCENTA is a colorimetric cephalosporin substrate for β-lactamases. Upon hydrolysis by β-lacatamases, CENTA turns from light yellow to chrome yellow, which can be quantified by colorimetric detection at 405 nm as a measure of β-lactamase activity.
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AZD-CO-Ph-PEG4-Ph-CO-AZD
0 ImagesCat. No.: HY-141808CAS No.: 2569143-72-0AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis.
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Avibactam sodium salt-13C5
0 ImagesCat. No.: HY-14879S2Purity: 99.9%Synonyms: NXL-104-13C5Avibactam sodium salt-13C5 (NXL-104-13C5) is 13C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
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Meropenem-vaborbactam
0 ImagesCat. No.: HY-111521CAS No.: 2031124-72-6Synonyms: CarbavanceMeropenem-vaborbactam (Carbavance) is a Carbapenem Antibiotic and Boronic acid-based beta-lactamase inhibitor, is a fixed-dose combination product with potent in vitro activity against Enterobacteriaceae that are Klebsiella pneumoniae carbapenemase producers. Meropenem-vaborbactam exhibits activity against Pseudomonas aeruginosa isolates , with an MIC50 of 0.5 μg/mL and an MIC90 of 8 μg/mL.
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Cefoxitin sodium (Standard)
0 ImagesSynonyms: MK-306 (Standard)Cefoxitin sodium (Standard) is the analytical standard of Cefoxitin sodium. This product is intended for research and analytical applications. Cefoxitin sodium is a cephalosporin-class antibiotic. Cefoxitin sodium is highly stable against β-Lactamase (HY-P2998). Cefoxitin sodium has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria.
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Cefotaxime (Standard)
0 ImagesSynonyms: Cefotaxim (Standard); HR-756 (Standard)Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.
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Brobactam sodium
0 ImagesBrobactam sodium is a potent synthetic wide spectrum β-lactamase inhibitor. Brobactam sodium has antibacterial activity.
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WCK-4234
0 ImagesWCK-4234 is a diazabicyclooctane β-lactamase inhibitor and susceptibility restorer. WCK-4234 lacks direct antibacterial activity. WCK-4234 inhibits class A, C, D β-lactamases and extended-spectrum β-lactamases to potentiate Imipenem (HY-B1369A) and Meropenem (HY-13678) activity against Gram-negative pathogens. WCK-4234 can be used for the research of gram-negative bacterial infections and β-lactamase-mediated carbapenem-resistant bacterial infections.
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Relebactam (Standard)
0 ImagesSynonyms: MK-7655 (Standard)Relebactam (Standard) is the analytical standard of Relebactam. This product is intended for research and analytical applications. Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity.
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Ceftazidime-d5
0 ImagesCat. No.: HY-B0593SSynonyms: GR20263-d5Ceftazidime-d5 (GR20263-d5) is the deuterium labeled Ceftazidime (HY-B0593). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.
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Avibactam tomilopil
0 ImagesSynonyms: ARX-1796; AV-006Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections.
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Pralurbactam
0 ImagesSynonyms: FL058Pralurbactam (FL058) is a β-lactamase (Beta-lactamase) inhibitor. Pralurbactam enhances the antibacterial activity of Imipenem against Mycobacterium abscessus. Pralurbactam reduces the pulmonary bacterial load in neutropenic mice infected with Mycobacterium abscessus. Pralurbactam can be used in research related to infections caused by Mycobacterium abscessus complex, Escherichia coli, and Klebsiella pneumoniae.
