Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
All Product Categories
-
Drug Derivative Inhibitors
(12)
View all products
-
Drug Derivative Agonist
(1)
View all products
-
Drug Derivative Activator
(1)
View all products
-
Drug Derivative Chemical
(1)
View all products
-
Drug Derivative Inducer
(1)
View all products
-
Drug Derivative Controls
(38)
View all products
-
Drug Derivative Substrate
(1)
View all products
-
Drug Derivative Related Products (4062)
Related Products (4062)
-
3'-O-Acetyl-akebia saponin D
0 ImagesCat. No.: HY-N17309CAS No.: 1621962-89-73'-O-Acetyl-akebia saponin D (compound 23) is a triterpenoid saponin found in the roots of Dipsacus asper (Radix Dipsaci).3'-O-Acetyl-akebia saponin D is an isomer of 4'-O-acetyl-akebia saponin D.
-
α-Isopropylaminopentiophenone hydrochloride
0 Imagesα-Isopropylaminopentiophenone hydrochloride is a α-aminoketone derivative.
-
L-Chlorozotocin
0 ImagesCat. No.: HY-122366CAS No.: 69839-80-1Synonyms: NSC-291322L-Chlorozotocin is an active compound.
-
Ch-319
0 ImagesCat. No.: HY-122894CAS No.: 2589088-07-1Ch-319 is a Triphenyltin (IV) carboxylate derivative. Ch-319 reduces androgen receptor expression, AKT and PRAS40 phosphorylation levels, and increases FOXO3a expression. Ch-319 increases Apoptosis. Ch-319 can be used in the research of prostate cancer.
-
Macaene
0 ImagesCat. No.: HY-N17472CAS No.: 405906-96-9Macaene is a natural product that can be found in Lepidium?meyenii?Walp..
-
Gibberellic acid, suitable for plant cell culture
0 ImagesGibberellic acid, suitable for plant cell culture (GA3, suitable for plant cell culture) is a natural plant growth regulator with oral bioactivity. Gibberellic acid, suitable for plant cell culture governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid, suitable for plant cell culture optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid, suitable for plant cell culture mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid, suitable for plant cell culture can be used in studies of plant growth, metabolism, and abiotic stress responses.
-
Nagrestipen
0 ImagesCat. No.: HY-P3627CAS No.: 166089-33-4
-
6-O-trans-p-Coumaroylshanzhiside methyl ester
0 ImagesCat. No.: HY-N2730CAS No.: 1246012-26-96-O-trans-p-Coumaroylshanzhiside methyl ester is a natural iridoid.
-
8,11-Octadecadienoicacid, methyl ester
0 ImagesCat. No.: HY-N19806CAS No.: 56599-58-78,11-Octadecadienoic acid, methyl ester is a polyunsaturated fatty acid methyl ester that can be extracted from castor seeds via direct ultrasonic transesterification.
-
TA-993
0 ImagesCat. No.: HY-125347CAS No.: 150591-06-3TA-993 is a compound that increases limb blood flow. Its effect of increasing limb blood flow is mediated through the sympathetic nervous system, but not through adrenergic receptors, and its mechanism of action on heart rate may be different.
-
[Glp5,Sar9] Substance P (5-11)
![[Glp5,Sar9] Substance P (5-11)](https://file.medchemexpress.com/product_pic/hy-p3905.gif "Click to View [Glp5,Sar9] Substance P (5-11) Product Detail")
0 ImagesCat. No.: HY-P3905CAS No.: 77128-78-0[Glp5,Sar9] Substance P (5-11) is a neuropeptide Substance P (HY-P0201) analogue specifically designed to interact with the Neurokinin-1 (NK1) receptor. [Glp5,Sar9] Substance P (5-11) modulates pain perception and inflammatory responses.
-
Peruvianoside I
0 ImagesCat. No.: HY-N16872CAS No.: 450407-24-6Peruvianoside I is a natural flavonoid.
-
(9R)-Exatecan
0 ImagesCat. No.: HY-13631NCAS No.: 2489613-17-2Synonyms: (9R)-DX8951f(9R)-Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan (HY-13631). Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
-
(-)-α-Cadinene
0 ImagesCat. No.: HY-N11238CAS No.: 24406-05-1(-)-α-Cadinene is a sesquiterpene hydrocarbon that can be isolated from Japanese hops. (-)-α-Cadinene is a natural product.
-
Rauvotetraphylline D
0 ImagesCat. No.: HY-N16944CAS No.: 73123-79-2Rauvotetraphylline D is a natural alkaloid.
-
12-O-Methylinophyllum A
0 ImagesCat. No.: HY-N13799CAS No.: 2131757-10-1Synonyms: (-)-12-Methoxyinophyllum A12-O-Methylinophyllum A ((-)-12-Methoxyinophyllum A) is a natural coumarin.
-
trans-Ditiliroside
0 ImagesCat. No.: HY-N16925CAS No.: 218605-31-3trans-Ditiliroside is a natural flavonoid.
-
A-119637
0 ImagesCat. No.: HY-120205CAS No.: 255713-47-4A-119637 is an active compound.
-
2'-Prenylisorhamnetin
0 ImagesCat. No.: HY-N13845CAS No.: 1932668-04-62'-Prenylisorhamnetin is a natural flavonoid.
