Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-78871S6

N-Methylpiperazine-d₃ hydrochloride
N-Methylpiperazine-d3 (hydrochloride) is a deuterated labeled N-Methylpiperazine.

HY-B0317S1

Amlodipine-d₄		99.28%
Amlodipine-d₄ is a deuterium labeled Amlodipine (HY-B0317). Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer.

HY-W653930

4,4'-Sulfonyldiphenol-¹³C₁₂
4,4'-Sulfonyldiphenol-¹³C₁₂ (Bisphenol S-¹³C₁₂) is ¹³C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-13011S

Alectinib-d₈
Alectinib-d₈ is the deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC₅₀ of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC₅₀s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

HY-Y0721S1

3-Bromofluorobenzene-d₄		99.75%
3-Bromofluorobenzene-d₄ (m-Bromofluorobenzene-d₄) is the deuterium labeled 3-Bromofluorobenzene.

HY-13636S1

Fulvestrant-d₅		99.66%
Fulvestrant-d₅ (ICI 182780-d₅) is a isotope of Fulvestrant (HY-13636). Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC₅₀ of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC₅₀ of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

HY-W653894

Tentoxin-d₃		98.23%
Tentoxin-d₃ is the deuterium-labeled Tentoxin (HY-N6717). Tentoxin-d₃ is a cyclic tetrapeptide isolated from Alternaria tenuis, acts as a herbicide, causes seedling chlorosis, inhibits cyclic photophosphorylation and functions as an energy transfer inhibitor.

HY-113161S1

L-Octanoylcarnitine-d₉
L-Octanoylcarnitine-d₉ is deuterium labeled L-Octanoylcarnitine. L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer. .

HY-B1095S1

Chlormadinone acetate-d₆-1		99.0%
Chlormadinone acetate-d₆-1 is deuterium labeled Chlormadinone acetate (HY-B1095). Chlormadinone acetate is a progestogen with potent progestogenic activity and antiandrogenic effects. Chlormadinone acetate acts on glucocorticoid receptor, progesterone receptor, androgen receptor, and GABA_A receptor. Chlormadinone acetate induces endometrial proliferation in estrogen-pretreated rabbits, inhibits testosterone-stimulated growth of the prostate and seminal vesicles in castrated rats, and reduces the thymus and adrenal weights in juvenile rats. Chlormadinone acetate is applicable to research related to diseases such as depression and reproductive metabolic disorders.

HY-B0859S1

MCPA-d₃		98.6%
MCPA-d₃ is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds.

HY-19542S1

C6 Ceramide-d₁₁		99.79%
C6 Ceramide-d₁₁ is deuterated labeled C6 Ceramide (HY-19542). C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects.

HY-W011824S

2′-O-Methyluridine-d₃		99.19%
2′-O-Methyluridine-d₃ is deuterium labeled 2′-O-Methyluridine (HY-W011824).2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer.

HY-B0928S

Homosalate-d₄		99.95%
Homosalate-d₄ is the deuterium labeled Homosalate. Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage.

HY-139959S

(±)12(13)-EpOME-d₄		99.9%
(±)12(13)-EpOME-d₄ is the deuterium labeled (±)12(13)-EpOME.

HY-W018004S

L-Homocitrulline-d₃		99.68%
L-Homocitrulline-d₃ is the deuterium labeled L-Homocitrulline. L-Homocitrulline is metabolized to homoarginine through homoargininosuccinate via the urea cycle pathway and its metabolic abnormality could lead to Lysinuric Protein Intolerance (LPI).

HY-N0565S1

Doxycycline-d₃ (hyclate) (major)
Doxycycline-d₃ hyclate (major) is the deuterium labeled Doxycycline hyclate (HY-N0565B). Doxycycline hyclate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline hyclate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline hyclate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline hyclate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline hyclate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline hyclate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers.

HY-W008630S

Decyltrimethylammonium-d₂₁ bromide		99.90%
N,N,N-Trimethyldecan-1-aminium-d₂₁ bromide is the deuterium labeled N,N,N-Trimethyldecan-1-aminium bromide.

HY-W086988S

5-Methyl-1H-benzotriazole-d₆
5-Methyl-1H-benzotriazole-d₆ (5-Methylbenzotriazole-d₆) is the deuterium labeled 5-Methyl-1H-benzotriazole (HY-W086988). 5-Methyl-1H-benzotriazole is a biological material or organic compound that can be used in life science research.

HY-110159S

Teriflunomide-d₄		99.98%
Teriflunomide-d₄ is deuterium labeled Teriflunomide.

HY-I0202S

1-Bromo-4-fluorobenzene-d₄		99.64%
1-Bromo-4-fluorobenzene-d₄ is the deuterium labeled 1-Bromo-4-fluorobenzene.

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