Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Related Products (375)
Related Products (375)
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BuChE-IN-2
0 ImagesCat. No.: HY-143413CAS No.: 2745118-93-6BuChE-IN-2 is an excellent butyrylcholinesterase (BuChE) inhibitor (IC50s of 1.28 μM and 0.67 μM for BuChE and NO). BuChE-IN-2 can inhibit the aggregation of Aβ, ROS formation and chelate Cu2+, exhibiting proper blood-brain barrier (BBB) penetration. BuChE-IN-2 has potential to research Alzheimer’s disease.
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Hydrangeifolin I
0 ImagesCat. No.: HY-N16742CAS No.: 88510-10-5Hydrangeifolin I is a natural phenolic compound.
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Ferroptosis-IN-26
0 ImagesCat. No.: HY-183589Ferroptosis-IN-26 is a CEPT1-targeting ferroptosis inhibitor. Ferroptosis-IN-26 enhances CEPT1-dependent phosphatidylcholine remodeling to enrich cellular membranes with monounsaturated fatty acid-containing phosphatidylcholine (PC-MUFA). Ferroptosis-IN-26 suppresses lipid peroxidation. Ferroptosis-IN-26 can be used for the research of acute liver injury.
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Luteolin 7-O-(6-O-malonyl-β-D-glucoside)
0 ImagesCat. No.: HY-N17495CAS No.: 98767-38-5Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research.
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PQM-244
0 ImagesCat. No.: HY-174848CAS No.: 316139-50-1PQM-244 (Compound 5c) is an orally active and multi-target modulator of TRPV1 and CB1 and CB2 receptors. PQM-244 has significant peripheral antinociceptive effects on both neurogenic and inflammatory phases. PQM-244 also has potential antioxidant activity with an IC50 of 14.15 µM for radical scavenging DPPH. PQM-244 can be used for chronic pain and inflammatory disease research, such as diabetes, atherosclerosis and Alzheimer’s disease.
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Bakkenolide Iva
0 ImagesCat. No.: HY-N21765CAS No.: 915289-61-1Bakkenolide Iva is a bakkenolide-type sesquiterpene. Bakkenolide Iva is isolated from the rhizomes of Petasites tricholobus. Bakkenolide Iva inhibits lipid peroxidation in rat brain homogenates and scavenges DPPH free radicals. Bakkenolide Iva protects cortical neurons against oxygen-glucose deprivation-induced injury and oxidative stress-induced neuronal injury. Bakkenolide Iva can be used in research on paralysis and allergic rhinitis.
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2,3,9,10-Tetrahydroxyberberine bromide
0 ImagesCat. No.: HY-N11962ACAS No.: 2847856-62-42,3,9,10-Tetrahydroxyberberine bromide is an acetylcholinesterase AChE inhibitor (IC50=7.8 μM). 2,3,9,10-Tetrahydroxyberberine bromide exhibits DPPH free radical scavenging activity (IC50=43 μM) and is applicable to research related to Alzheimer's disease.
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Eleocharin E
0 ImagesCat. No.: HY-N21598CAS No.: 1619977-00-2Eleocharin E is a flavanone found in the peel of Eleocharis tuberosa and acts as a scavenger of DPPH radicals. Eleocharin E exhibits reducing power activity. Eleocharin E can be used in research on oxidative stress.
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(+)-Isoampelopsin F
0 ImagesCat. No.: HY-N13793CAS No.: 354553-38-1(+)-Isoampelopsin F is an oligostilbene compound that exists in the roots of Caragana sinica. (+)-Isoampelopsin F does not exhibit significant DPPH radical scavenging or lipid peroxidation inhibitory activity, with IC50 values all >200 μM.
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(2S,3S)-2-Geranyl-2,7-dimethylchromane-3,5-diol
0 ImagesCat. No.: HY-N17367CAS No.: 1245649-15-3(2S,3S)-2-Geranyl-2,7-dimethylchromane-3,5-diol is a phenolic compound that can be found in Boletus pseudocalopus. (2S,3S)-2-Geranyl-2,7-dimethylchromane-3,5-diol exhibits radical-scavenging activity.
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3,4,6-Tri-O-galloyl-D-glucose
0 ImagesCat. No.: HY-N17215CAS No.: 99523-99-6Synonyms: 3,4,6-Trigalloylglucose3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase (porcine α-amylase IC50 = 334.6 μM; Ki = 307.5 μM) and α-glucosidase (yeast α-glucosidase IC50 = 46.5 μM; Ki = 39.9 μM) mixed type inhibitor. 3,4,6-Tri-O-galloyl-D-glucose exhibits free radical scavenging ability, ferric-reducing power, and antioxidant activity. 3,4,6-Tri-O-galloyl-D-glucose can be used for the research of diabetes.
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Massonianoside E
0 ImagesCat. No.: HY-N18052CAS No.: 872037-79-1Massonianoside E is an antioxidant that has been found to be present in the fruits of Viburnum rhytidophyllum Hemsl. Massonianoside E can exert antioxidant activity in DPPH, ABTS and PTIO assays.
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2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone
0 ImagesCat. No.: HY-N16606CAS No.: 123999-38-22,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone (Compound 8) is an Acetophenone (HY-Y0989) derivative found in Acronychia oligophlebia. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone exhibits anti-inflammatory and antioxidant activities. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can inhibit LPS (HY-D1056)-induced NO production (IC50 = 34.5 μM) and scavenge DPPH free radical (SC50 = 0.15 mM). 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can be used for the research of inflammation.
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Dulcisxanthone B
0 ImagesCat. No.: HY-N16515CAS No.: 869669-62-5Dulcisxanthone B is an antioxidant agent with free radical scavenging against DPPH (IC50 of 0.39 mM) and lipid peroxidation inhibition (IC50 of 024 μM).
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Antitumor agent-68
0 ImagesCat. No.: HY-146169CAS No.: 2566497-96-7Antitumor agent-68 is a potent tubulin inhibitor. Antitumor agent-68 shows potent anticancer activity with IC50s of 3.6 and 3.8 μM for HeLa and MCF-7 cells, respectively. Antitumor agent-68 exhibits good scavenging activity of ROS and DPPH radical in a dose-dependent manner. Antitumor agent-68 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene
0 ImagesCat. No.: HY-N10927CAS No.: 1608462-12-92,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC50 value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity.
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MAO-B-IN-48
0 ImagesCat. No.: HY-175523MAO-B-IN-48 is a selective MAO-B inhibitor (IC50 = 0.09 μM, Ki = 0.02 μM). MAO-B-IN-48 exhibits inhibitory activity against hBChE (IC50 = 1.10 μM, Ki = 0.43 μM) and AChE (IC50 = 0.56 μM, Ki = 0.14 μM). MAO-B-IN-48 suppresses self-induced aggregation of toxic β-amyloid peptides and exerts antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. MAO-B-IN-48 can be used for the study of Alzheimer's disease (AD).
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Bispyrayafoline
0 ImagesCat. No.: HY-N19719CAS No.: 1715114-37-6Bispyrayafoline is a pyrrolidone and antioxidant with an IC50 value of 13.85 μM against DPPH. Bispyrayafoline can be found in the leaves of Murraya koenigii (Linn.) Spreng. Bispyrayafoline's antioxidant activity is concentration-dependent but time-independent. Bispyrayafoline can be utilized in studies concerning oxidative damage.
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Odoratumone A
0 ImagesCat. No.: HY-N17551CAS No.: 1198306-72-7Odoratumone A (Compound 1/11) is a homoisoflavonoid identified in the rhizomes of Polygonatum odoratum (Mill.) Druce. Odoratumone A exhibits DPPH free radical scavenging activity (IC50 = 32.8 μg/mL) and exerts antioxidant properties. Odoratumone A is applicable for antioxidant research.
