2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11061):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10410R
    TG101209 (Standard)
    TG101209 (Standard) is the analytical standard of TG101209 (HY-10410). This product is intended for research and analytical applications. TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations.
    TG101209 (Standard)
  • HY-W011035R
    Dodecamethylpentasiloxane (Standard)
    Dodecamethylpentasiloxane (Standard) is the analytical standard of Dodecamethylpentasiloxane. This product is intended for research and analytical applications. Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug.
    Dodecamethylpentasiloxane (Standard)
  • HY-Z8616R
    3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine maleate (Chlorphenamine Impurity) (Standard)
    3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine maleate (Chlorphenamine Impurity) (Standard) is the analytical standard of 3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine maleate (Chlorphenamine Impurity). This product is intended for research and analytical applications.
    3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine maleate (Chlorphenamine Impurity) (Standard)
  • HY-10502R
    Tipifarnib (Standard)
    Tipifarnib (Standard) is the analytical standard of Tipifarnib (HY-10502). This product is intended for research and analytical applications. Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
    Tipifarnib (Standard)
  • HY-B1324R
    Oxiconazole nitrate (Standard)
    Oxiconazole nitrate (Standard) is the analytical standard of Oxiconazole nitrate. This product is intended for research and analytical applications. Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.
    Oxiconazole nitrate (Standard)
  • HY-108448R
    N-Oleoyldopamine (Standard)
    N-Oleoyldopamine (Standard) is the analytical standard of N-Oleoyldopamine (HY-108448). This product is intended for research and analytical applications. N-Oleoyldopamine (OLDA) is a product of condensation of oleic acid and dopamine (DA) and an endogenous TRPV1 selective agonist. N-Oleoyldopamine (OLDA) can crosses the blood-brain barrier. N-oleoyl-dopamine protects the heart against ischemia-reperfusion injury via activation of TRPV1.
    N-Oleoyldopamine (Standard)
  • HY-121935R
    Tecnazene (Standard)
    Tecnazene (Standard) is the analytical standard of Tecnazene. This product is intended for research and analytical applications. Tecnazene is a dinitroaromatic fungicide and plant growth regulator. Tecnazene binds irreversibly to human skin tissues and exhibits acute toxicity in Rattus norvegicus (brown rat). Tecnazene exerts sprouting-inhibiting and antifungal activities by inhibiting the sprouting of potato tuber buds and blocking the growth and reproduction of fungi that cause dry rot. Tecnazene has significant antifungal and sprouting-inhibiting activities, and shows high toxicity to aquatic organisms such as freshwater fish and crustaceans. Tecnazene is used for sprouting inhibition and dry rot control during potato storage.
    Tecnazene (Standard)
  • HY-W009565R
    2-[(Diphenylmethyl)thio]acetamide (Standard)
    2-[(Diphenylmethyl)thio]acetamide (Standard) is the analytical standard of 2-[(Diphenylmethyl)thio]acetamide. This product is intended for research and analytical applications.
    2-[(Diphenylmethyl)thio]acetamide (Standard)
  • HY-103068R
    Diethyl-pythiDC (Standard)
    Diethyl-pythiDC (Standard) is the analytical standard of Diethyl-pythiDC (HY-103068). This product is intended for research and analytical applications. Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).
    Diethyl-pythiDC (Standard)
  • HY-N2450R
    Sulforaphene (Standard)
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
    Sulforaphene (Standard)
  • HY-106542AR
    Eberconazole nitrate (Standard)
    Eberconazole nitrate (Standard) is the analytical standard of Eberconazole nitrate. This product is intended for research and analytical applications. Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis.
    Eberconazole nitrate (Standard)
  • HY-112061R
    8-OH-DPAT (Standard)
    8-OH-DPAT (Standard) is the analytical standard of 8-OH-DPAT. This product is intended for research and analytical applications. 8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
    8-OH-DPAT (Standard)
  • HY-13271R
    Tubastatin A Hydrochloride (Standard)
    Tubastatin A (Hydrochloride) (Standard) is the analytical standard of Tubastatin A (Hydrochloride). This product is intended for research and analytical applications. Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    Tubastatin A Hydrochloride (Standard)
  • HY-10821R
    Raltitrexed (Standard)
    Raltitrexed (Standard) is the analytical standard of Raltitrexed. This product is intended for research and analytical applications. Raltitrexed is an antimetabolite agent used in chemotherapy, acting by inhibiting thymidylate synthase.
    Raltitrexed (Standard)
  • HY-Z6843R
    Noradrenalone impurity 1 hydrochloride (Standard)
    2-Amino-1-(3,4-dihydroxyphenyl)ethanone hydrochloride (Noradrenaline Impurity) (Standard) is the analytical standard of 2-Amino-1-(3,4-dihydroxyphenyl)ethanone hydrochloride (Noradrenaline Impurity). This product is intended for research and analytical applications.
    Noradrenalone impurity 1 hydrochloride (Standard)
  • HY-103528R
    SCS (Standard)
    SCS (Standard) is the analytical standard of SCS (HY-103528). This product is intended for research and analytical applications. SCS (Salicylidene salicylhydrazide) is a potent, allosteric and selective inhibitor of β1-containing GABAA receptors with an IC50 of 32 nM against α2β1γ1θ by VIPR measurement. SCS is also a chelator of metal ions.
    SCS (Standard)
  • HY-102028R
    KY1220 (Standard)
    KY1220 (Standard) is the analytical standard of KY1220 (HY-102028). This product is intended for research and analytical applications. KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway, with an IC50 of 2.1 μM in HEK293 reporter cells.
    KY1220 (Standard)
  • HY-W004570R
    5-Nitro-1,10-phenanthroline (Standard)
    5-Nitro-1,10-phenanthroline (Standard) (5-NP (Standard)) is the analytical standard of 5-Nitro-1,10-phenanthroline (HY-W004570). This product is intended for research and analytical applications. 5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells.
    5-Nitro-1,10-phenanthroline (Standard)
  • HY-103244R
    CITCO (Standard)
    CITCO (Standard) is the analytical standard of CITCO (HY-103244). This product is intended for research and analytical applications. CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
    CITCO (Standard)
  • HY-W027951R
    N,N'-Dimethylthiourea (Standard)
    N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action.
    N,N'-Dimethylthiourea (Standard)