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Cat. No.: HY-153192R

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Nerandomilast (Standard)

Name: Nerandomilast (Standard)
Brand: MedChemExpress
SKU: HY-153192R
Availability: PreOrder

(Synonyms: BI 1015550 (Standard))

Nerandomilast (Standard) is the analytical standard of Nerandomilast (HY-153192). This product is intended for research and analytical applications. Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC₅₀ value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD).

For research use only. We do not sell to patients.

CAS No.: 1423719-30-5
Formula: C₂₀H₂₅ClN₆O₂S
Molecular Weight:448.97

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nerandomilast (Standard) Chemical Structure

CAS No.: 1423719-30-5

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1423719-30-5
Molecular Weight 448.97
Formula C₂₀H₂₅ClN₆O₂S
SMILES

O=[S@]1C2=C(CC1)N=C(N3CCC(CC3)C4=NC=C(C=N4)Cl)N=C2NC5(CO)CCC5
Synonyms

BI 1015550 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Pouzet P A, et al. Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma. United States. US9150586.

[2]. Herrmann FE, et al. BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2022 Apr 20;13:838449. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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