Vinconate
Vinconate is an indolonaphthyridine derivative and can stimulate the muscariic acetylcholine receptor.
For research use only. We do not sell to patients.
- CAS No.: 70704-03-9
- Formula: C18H20N2O2
- Molecular Weight:296.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
muscariic acetylcholine receptor[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 70704-03-9
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Molecular Weight 296.36
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Formula C18H20N2O2
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SMILES
O=C(C1=CCC2N(CC)CCC3=C2N1C4=C3C=CC=C4)OC
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Synonyms
Chanodesethylapovincamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
344 male rats, 6 months (adult) and 24 months (aged) of age, are allowed food and water ad lib throughout the experiments. Rats are divided into four groups; (1) 6-month-old; (2) vehicle (distilled water) is administered intraperitoneally (i.p.) once a day for 4 weeks before decapitation; (3) Vinconate at a dose of 10 mg/kg is administered i.p. once a day for 4 weeks before decapitation; (4) Vinconate at a dose of 30 mg/kg is administered i.p. once a day for 4 weeks before decapitation. Rats in groups (2) to (4) are 24 months old. Each group contains 6 to 7 rats. In addition, there are no significant differences among the three aged animal groups in body weight after drug or vehicle treatment[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
References
[1]. Iino T, et al. Effect of vinconate, an indolonaphthyridine derivative, on dopamine and serotonin concentrations in dialysate from the striatum of freely moving rats: brain microdialysis studies. J Pharmacol Exp Ther. 1996 Aug;278(2):614-9. [Content Brief]
[2]. Araki T, et al. Effects of vinconate on neurotransmitter receptor systems in aged rat brain. Environ Toxicol Pharmacol. 1996 Dec 20;2(4):343-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Vinconate Related Classifications
HY-U00316 Related Classifications
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