2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. A 331440 hydrochloride

A 331440 hydrochloride is a histamine H3 receptor antagonist. A 331440 hydrochloride binds potently and selectively to human and rat histamine H3 receptors (Ki≤25 nM). A 331440 hydrochloride can be used for antiobesity research.

For research use only. We do not sell to patients.

A 331440 hydrochloride

A 331440 hydrochloride Chemical Structure

CAS No. : 1049740-32-0

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Based on 1 publication(s) in Google Scholar

Other Forms of A 331440 hydrochloride:

A 331440 hydrochloride Related Antibodies

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Description

A 331440 hydrochloride is a histamine H3 receptor antagonist. A 331440 hydrochloride binds potently and selectively to human and rat histamine H3 receptors (Ki≤25 nM). A 331440 hydrochloride can be used for antiobesity research[1].

Molecular Weight

422.39

Formula

C22H29Cl2N3O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

[H]Cl.[H]Cl.CN(C)[C@H](CC1)CN1CCCOC2=CC=C(C3=CC=C(C=C3)C#N)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (23.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3675 mL 11.8374 mL 23.6748 mL
5 mM 0.4735 mL 2.3675 mL 4.7350 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3675 mL 11.8374 mL 23.6748 mL 59.1870 mL
5 mM 0.4735 mL 2.3675 mL 4.7350 mL 11.8374 mL
10 mM 0.2367 mL 1.1837 mL 2.3675 mL 5.9187 mL
15 mM 0.1578 mL 0.7892 mL 1.5783 mL 3.9458 mL
20 mM 0.1184 mL 0.5919 mL 1.1837 mL 2.9594 mL
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A 331440 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A 3314401049740-32-0A331440A-331440Histamine Receptorantiobesityhistaminehigh-fat dietweightInhibitorinhibitorinhibit

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A 331440 hydrochloride
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