A-74932 hydrochloride
A-74932 hydrochloride is a potent Top II inhibitor with antitumor activity. A-74932 hydrochloride inhibits the catalytic activity of mammalian DNA topoisomerase II. A-74932 hydrochloride can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 148201-60-9
- Formula: C25H26ClFN4O5
- Molecular Weight:516.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Topoisomerase Isoforms
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Biological Activity
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Topoisomerase II |
Chemical Information
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CAS No. 148201-60-9
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Molecular Weight 516.95
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Formula C25H26ClFN4O5
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SMILES
O=C(C1=CN2C3=C(C(N4C(NC(C(N)CCC)=O)CCC4)=C(F)C=C3C1=O)OC5=CC=CC=C25)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Snyder RD. Use of catalytic topoisomerase II inhibitors to probe mechanisms of chemical-induced clastogenicity in Chinese hamster V79 cells. Environ Mol Mutagen. 2000;35(1):13-21. [Content Brief]
[2]. Permana PA, et al. Quinobenoxazines: a class of novel antitumor quinolones and potent mammalian DNA topoisomerase II catalytic inhibitors. Biochemistry. 1994 Sep 20;33(37):11333-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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