2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. A-74932 hydrochloride

A-74932 hydrochloride is a potent Top II inhibitor with antitumor activity. A-74932 hydrochloride inhibits the catalytic activity of mammalian DNA topoisomerase II. A-74932 hydrochloride can be used for cancer research.

For research use only. We do not sell to patients.

A-74932 hydrochloride

A-74932 hydrochloride Chemical Structure

CAS No. : 148201-60-9

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A-74932 hydrochloride Related Antibodies

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Description

A-74932 hydrochloride is a potent Top II inhibitor with antitumor activity. A-74932 hydrochloride inhibits the catalytic activity of mammalian DNA topoisomerase II. A-74932 hydrochloride can be used for cancer research[1][2].

IC50 & Target[1]

Topoisomerase II

 

Molecular Weight

516.95

Formula

C25H26ClFN4O5
CAS No.
SMILES

O=C(C1=CN2C3=C(C(N4C(NC(C(N)CCC)=O)CCC4)=C(F)C=C3C1=O)OC5=CC=CC=C25)O.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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A-74932 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A-74932148201-60-9A74932A 74932Topoisomerasemammalian DNA topoisomerase IIInhibitorinhibitorinhibit

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