2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Ac4GalNAlk

Ac4GalNAlk is a weakly alkyne-labeled reagent for metabolic oligosaccharide engineering (MOE) that can be used to detect protein glycosylation. MOE reagents can be activated by cellular biosynthetic machinery into nucleotide sugars, which can be further traced through the introduction of glycoproteins in bioorthogonal chemistry. Ac4GalNAlk promotes nucleotide-sugar biosynthesis and increases bioorthogonal cell surface markers.

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Ac4GalNAlk

Ac4GalNAlk Chemical Structure

CAS No. : 1810852-60-8

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Based on 1 publication(s) in Google Scholar

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Description

Ac4GalNAlk is a weakly alkyne-labeled reagent for metabolic oligosaccharide engineering (MOE) that can be used to detect protein glycosylation. MOE reagents can be activated by cellular biosynthetic machinery into nucleotide sugars, which can be further traced through the introduction of glycoproteins in bioorthogonal chemistry. Ac4GalNAlk promotes nucleotide-sugar biosynthesis and increases bioorthogonal cell surface markers[1].

Molecular Weight

427.40

Formula

C19H25NO10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(O[C@@H]1[C@H](C(O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OC(C)=O)NC(CCC#C)=O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Ac4GalNAlk Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac4GalNAlk1810852-60-8Endogenous MetaboliteMetabolic oligosaccharide engineeringMOEprotein glycosylationInhibitorinhibitorinhibit

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