AChE/BChE-IN-17
AChE/BChE-IN-17 (compound 8m) is a potent and non-competitiveAChE and BChE inhibitor, with IC50 values of 125.06 nM and 119.68 nM, respectively. AChE/BChE-IN-17 also inhibits α-glucosidase, with an IC50 of 41050 nM.
For research use only. We do not sell to patients.
- CAS No.: 3026229-55-7
- Formula: C28H25N3O4
- Molecular Weight:467.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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AChE 125.06 ± 2 nM (IC50) |
BChE 119.68 ± 2 nM (IC50) |
Chemical Information
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CAS No. 3026229-55-7
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Molecular Weight 467.52
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Formula C28H25N3O4
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SMILES
O=[N+]([O-])C1=CC=C2C(N=C(/C(CCC3)=C/C4=CC=C(OC)C=C4)C3=C2NC5=CC=C(OC)C=C5)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)