AChE/BChE-IN-26
AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM and 4.11 μM against eeAChE and eqBChE, respectively. AChE/BChE-IN-26 has antioxidant activity and can be used in the research of diseases such as Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C29H21F6N5O2S2
- Molecular Weight:649.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
eqBCHE 4.11 μM (IC50) |
Chemical Information
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Molecular Weight 649.63
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Formula C29H21F6N5O2S2
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SMILES
O=C(NCC1=CC(C(NCC2=CC=C(C(F)(F)F)C=C2)=O)=CC=C1)CSC3=NN4C(S3)=NC(C5=CC=C(C(F)(F)F)C=C5)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)