country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-189802

Copy Link Print Information

AChE/BChE-IN-40

AChE/BChE-IN-40 is an AChE/BChE inhibitor. AChE/BChE-IN-40 reduces acetylcholine hydrolysis, with IC₅₀ values of 35.31 nM and 28.91 nM against Electrophorus electricus AChE and equine BChE, respectively. AChE/BChE-IN-40 can be used in the study of Alzheimer's disease.

For research use only. We do not sell to patients.

Formula: C₂₄H₃₅N₃O₃
Molecular Weight:413.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AChE/BChE-IN-40 Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

electric eel AChE

35.31 nM (IC₅₀)

eqBCHE

28.91 nM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
MDA-MB-231	IC50	100 μM	Cytotoxicity against human MDA-MB-231 cells assessed as viability reduction incubated 72 hrs by MTT assay. Cytotoxicity against human MDA-MB-231 cells assessed as viability reduction incubated 72 hrs by MTT assay.	42730239
BT-20	IC50	100 μM	Cytotoxicity against human BT-20 cells assessed as viability reduction incubated 72 hrs by MTT assay. Cytotoxicity against human BT-20 cells assessed as viability reduction incubated 72 hrs by MTT assay.	42730239
HT-29	IC50	65.74 μM	Cytotoxicity against human HT-29 cells assessed as viability reduction incubated 72 hrs by MTT assay. Cytotoxicity against human HT-29 cells assessed as viability reduction incubated 72 hrs by MTT assay.	42730239
MCF7	IC50	100 μM	Cytotoxicity against human MCF-7 cells assessed as viability reduction incubated 72 hrs by MTT assay. Cytotoxicity against human MCF-7 cells assessed as viability reduction incubated 72 hrs by MTT assay.	42730239
BT-549	IC50	100 μM	Cytotoxicity against human BT-549 cells assessed as viability reduction incubated 72 hrs by MTT assay. Cytotoxicity against human BT-549 cells assessed as viability reduction incubated 72 hrs by MTT assay.	42730239

In Vitro

AChE/BChE-IN-40 (ECB) (0-100 μM; 72 h) shows moderate cytotoxicity in HT-29 colon cancer cells (IC₅₀ 65.74 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Alzheimer’s Disease Modeling

Chemical Information

Molecular Weight 413.55
Formula C₂₄H₃₅N₃O₃
SMILES

CCC1=CC=CC2=C1NC3=C2CCOC3(CC)CC(NCCCN4CCOCC4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Comert Onder F, et al. Design, Synthesis, In Vitro Biological Evaluation, and In Silico Analyses of Novel Pyrano[3,4‑b]indole-Containing Compounds as Promising Multitarget Candidates for Alzheimer's Disease and Cancer Therapy. ACS Omega. 2026 Aug 26;11(35):52714-52730.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote