AChE-IN-104
AChE-IN-104 (compound 3e) is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 8.01 µM. AChE-IN-104 also inhibits BChE and MAO-A with IC50s of 65.41 µM and 1.51 µM, respectively. AChE-IN-104 can be used for Alzheimer’s disease (AD) research.
For research use only. We do not sell to patients.
- Formula: C20H15F3N2O4
- Molecular Weight:404.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
MAO-A 1.51 μM (IC50) |
AChE 8.01 μM (IC50) |
BChE 65.41 μM (IC50) |
Chemical Information
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Molecular Weight 404.34
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Formula C20H15F3N2O4
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SMILES
COC1=C(OC(C(/C(C)=N/NC(C2=CC=C(C(F)(F)F)C=C2)=O)=C3)=O)C3=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-104 Related Classifications
HY-180552 Related Classifications
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