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Cat. No.: HY-P4002

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Adamtsostatin 18

Adamtsostatin 18 is an anti-angiogenic peptide derived from proteins containing type I thrombospondin motifs. Adamtsostatin 18 inhibits cell migration and proliferation.

For research use only. We do not sell to patients.

CAS No.: 929554-95-0
Formula: C₈₉H₁₄₁N₂₉O₂₉S₂
Molecular Weight:2145.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Adamtsostatin 18 Chemical Structure

CAS No.: 929554-95-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Adamtsostatin 18 is an anti-angiogenic peptide derived from proteins containing type I thrombospondin motifs. Adamtsostatin 18 inhibits cell migration and proliferation^[1].

In Vitro

Adamtsostatin 18 ( 0.01, 0.1, 1, 10, 20, 30, 40 µg/mL; 3 days) inhibits cell proliferation in HUVECs^[1].
Adamtsostatin 18 (10, 30 µg/mL; 20 h) inhibits the migration of the endothelial cells in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

HUVECs
Concentration:

0.01, 0.1, 1, 10, 20, 30, 40 µg/mL
Incubation Time:

3 days
Result:

Inhibitted the cell proliferation.

Chemical Information

CAS No. 929554-95-0
Molecular Weight 2145.38
Formula C₈₉H₁₄₁N₂₉O₂₉S₂
Sequence Shortening

SKWSECSRTCGGGVKFQER
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karagiannis ED, et al. Anti-angiogenic peptides identified in thrombospondin type I domains. Biochem Biophys Res Commun. 2007 Jul 20;359(1):63-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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