country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N0701B

Copy Link Print Information

(+)-Asarinin

(+)-Asarinin (Isosesamin) is a lignan that can be found in Acronychia mulleri. (+)-Asarinin exhibits antitubercular and antimycobacterial activities.

For research use only. We do not sell to patients.

CAS No.: 133-03-9
Formula: C₂₀H₁₈O₆
Molecular Weight:354.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(+)-Asarinin Chemical Structure

CAS No.: 133-03-9

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

(+)-Asarinin (Isosesamin) is a lignan that can be found in Acronychia mulleri. (+)-Asarinin exhibits antitubercular and antimycobacterial activities^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	EC₅₀	>60 μM Compound: 5	Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay	[PMID: 22381047]
HepG2	IC₅₀	7.1 μM Compound: 5	Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis	[PMID: 22381047]
NIH3T3	IC₅₀	0.2 μM Compound: 1	Cytotoxicity against murine 3T3 cells by MTT assay Cytotoxicity against murine 3T3 cells by MTT assay	[PMID: 17253847]

In Vitro

(+)-Asarinin inhibits mycobacterium tuberculosis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 133-03-9
Molecular Weight 354.35
Formula C₂₀H₁₈O₆
SMILES

[H][C@]1(CO[C@@H]2C3=CC=C4OCOC4=C3)[C@]2([H])CO[C@H]1C5=CC=C6OCOC6=C5
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Esterhuizen LL, et, al. Antimicrobial compounds from Coleonema album (Rutaceae). Z Naturforsch C J Biosci. 2006 Jul-Aug;61(7-8):489-98. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote