AF-1
AF-1 is a azole-based near-infrared fluorescence diagnostic probe with an emission wavelength of 632 nm. AF-1 selectively accumulates in fungal cell membranes at physiological pH. AF-1 targets and induces Autophagy. AF-1 exhibits antifungal activity and sensitivity to autophagy-related pH.
For research use only. We do not sell to patients.
- Formula: C62H64F4N14O3
- Molecular Weight:1129.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 1129.26
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Formula C62H64F4N14O3
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SMILES
FC1=CC(F)=CC=C1C(CN2C=NC=N2)(CN3C=C(N=N3)CCCN4C5=C(C(C)(/C4=C\C=C6CCC/C(C/6=O)=C\C=C7C(C)(C8=C(C=CC=C8)N/7CCCC(N=N9)=CN9CC(O)(CN%10C=NC=N%10)C%11=CC=C(C=C%11F)F)C)C)C=CC=C5)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AF-1 Related Classifications
HY-D2977 Related Classifications
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