Alismanol M
Alismanol M is a farnesoid X receptor (FXR) agonist with an EC50 value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale. Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis.
For research use only. We do not sell to patients.
- CAS No.: 2408810-59-1
- Formula: C30H48O6
- Molecular Weight:504.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
50.25 μM
Compound: 37
|
Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay
Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay
|
[PMID: 31494470] |
Chemical Information
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CAS No. 2408810-59-1
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Molecular Weight 504.70
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Formula C30H48O6
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SMILES
C[C@@]12[C@@]3(C([C@](O)(CC3)[C@H](C)C[C@H](O)[C@@H](O)C(C)(O)C)=CC([C@@]1([H])[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC2)C)=O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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