Alloferon 1
Based on 1 Customer Validation
Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera).
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 347884-61-1
- Formula: C52H76N22O16
- Molecular Weight:1265.30
-
Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
-
CAS No. 347884-61-1
-
Appearance Solid
-
Molecular Weight 1265.30
-
Formula C52H76N22O16
-
Color White to off-white
-
Sequence
His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly
-
Sequence Shortening
HGVSGHGQHGVHG
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : ≥ 100 mg/mL (79.03 mM)
DMSO : 4.55 mg/mL (3.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Chernysh S, et al. Antiviral and antitumor peptides from insects. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32. [Content Brief]
[2]. Zhang X, et al. Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice. Sci Rep. 2022 Oct 6;12(1):16689. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 0.7903 mL | 3.9516 mL | 7.9033 mL | 19.7582 mL |
| H2O | 5 mM | 0.1581 mL | 0.7903 mL | 1.5807 mL | 3.9516 mL |
| 10 mM | 0.0790 mL | 0.3952 mL | 0.7903 mL | 1.9758 mL | |
| 15 mM | 0.0527 mL | 0.2634 mL | 0.5269 mL | 1.3172 mL | |
| 20 mM | 0.0395 mL | 0.1976 mL | 0.3952 mL | 0.9879 mL | |
| 25 mM | 0.0316 mL | 0.1581 mL | 0.3161 mL | 0.7903 mL | |
| 30 mM | 0.0263 mL | 0.1317 mL | 0.2634 mL | 0.6586 mL | |
| 40 mM | 0.0198 mL | 0.0988 mL | 0.1976 mL | 0.4940 mL | |
| 50 mM | 0.0158 mL | 0.0790 mL | 0.1581 mL | 0.3952 mL | |
| 60 mM | 0.0132 mL | 0.0659 mL | 0.1317 mL | 0.3293 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.