2. Peptides
  3. Alloferon 1

Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera).

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Custom Peptide Synthesis

Alloferon 1 Chemical Structure

Alloferon 1 Chemical Structure

CAS No. : 347884-61-1

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1 mg USD 90 In-stock
5 mg USD 225 In-stock
10 mg USD 340 In-stock
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Description

Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1][2][3].

Molecular Weight

1265.30

Formula

C52H76N22O16
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly
Sequence Shortening

HGVSGHGQHGVHG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (79.03 mM)

DMSO : 4.55 mg/mL (3.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7903 mL 3.9516 mL 7.9033 mL
5 mM 0.1581 mL 0.7903 mL 1.5807 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.97%

COA (245 KB) LCMS (96 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 0.7903 mL 3.9516 mL 7.9033 mL 19.7582 mL
H2O 5 mM 0.1581 mL 0.7903 mL 1.5807 mL 3.9516 mL
10 mM 0.0790 mL 0.3952 mL 0.7903 mL 1.9758 mL
15 mM 0.0527 mL 0.2634 mL 0.5269 mL 1.3172 mL
20 mM 0.0395 mL 0.1976 mL 0.3952 mL 0.9879 mL
25 mM 0.0316 mL 0.1581 mL 0.3161 mL 0.7903 mL
30 mM 0.0263 mL 0.1317 mL 0.2634 mL 0.6586 mL
40 mM 0.0198 mL 0.0988 mL 0.1976 mL 0.4940 mL
50 mM 0.0158 mL 0.0790 mL 0.1581 mL 0.3952 mL
60 mM 0.0132 mL 0.0659 mL 0.1317 mL 0.3293 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alloferon 1347884-61-1Alloferon1Alloferon-1Othersantiviralantitumoralnatural cytotoxicitylymphocytesIFN synthesisP388paw edemaosteoporosisInhibitorinhibitorinhibit

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