Amino-PEG3-C2-Amine
Based on 1 Customer Validation
Amino-PEG3-C2-Amine is a PEG-based (3 units) PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.37%
- CAS No.: 929-75-9
- Formula: C8H20N2O3
- Molecular Weight:192.26
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 929-75-9
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Appearance Liquid (Density: 1.2892 g/cm3)
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Molecular Weight 192.26
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Formula C8H20N2O3
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Color Colorless to light yellow
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SMILES
NCCOCCOCCOCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (520.13 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (520.13 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (265 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2013 mL | 26.0065 mL | 52.0129 mL | 130.0323 mL |
| 5 mM | 1.0403 mL | 5.2013 mL | 10.4026 mL | 26.0065 mL | |
| 10 mM | 0.5201 mL | 2.6006 mL | 5.2013 mL | 13.0032 mL | |
| 15 mM | 0.3468 mL | 1.7338 mL | 3.4675 mL | 8.6688 mL | |
| 20 mM | 0.2601 mL | 1.3003 mL | 2.6006 mL | 6.5016 mL | |
| 25 mM | 0.2081 mL | 1.0403 mL | 2.0805 mL | 5.2013 mL | |
| 30 mM | 0.1734 mL | 0.8669 mL | 1.7338 mL | 4.3344 mL | |
| 40 mM | 0.1300 mL | 0.6502 mL | 1.3003 mL | 3.2508 mL | |
| 50 mM | 0.1040 mL | 0.5201 mL | 1.0403 mL | 2.6006 mL | |
| 60 mM | 0.0867 mL | 0.4334 mL | 0.8669 mL | 2.1672 mL | |
| 80 mM | 0.0650 mL | 0.3251 mL | 0.6502 mL | 1.6254 mL | |
| 100 mM | 0.0520 mL | 0.2601 mL | 0.5201 mL | 1.3003 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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