Anisindione (Standard)
Anisindione (Standard) is the analytical standard of Anisindione (HY-B0924). This product is intended for research and analytical applications. Anisindione is an anticoagulant, a GGCX inhibitor, and a VKORC1 inhibitor. Anisindione directly occupies the vitamin K binding pocket of γ-glutamyl carboxylase (GGCX) and acts as a competitive antagonist of GGCX. Anisindione reduces plasma prothrombin activity. The effect of Anisindione can be interrupted by phytonadione, and it lacks hepatobiliary or hematological toxicity, making it useful for research on thrombosis, deep vein thrombosis, and pulmonary embolism.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 117-37-3
- Formula: C16H12O3
- Molecular Weight:252.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 117-37-3
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Molecular Weight 252.26
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Formula C16H12O3
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SMILES
O=C1C(C2=CC=C(OC)C=C2)C(C3=C1C=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Grosset AB, et al. Anticoagulation with anisindione in patients who are intolerant of warfarin. Am J Hematol. 1994;46(2):138-140. [Content Brief]
[3]. Wu K, et al. Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase. Nature communications. 2025 Nov 25;16(1):10480. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)