Antibacterial agent 376
Antibacterial agent 376 is an antibacterial agent. Antibacterial agent 376 exhibits antibacterial efficacy against S. aureus and E. coli. Antibacterial agent 376 induces mild hepatic alterations, including slight inflammatory cell infiltration, moderate vacuolar degeneration, and moderate hepatocyte enlargement, while the overall liver architecture remains largely preserved. Antibacterial agent 376 induces mild renal alterations, including vascular congestion, limited inflammatory cell infiltration, and mild tubular degeneration, while the overall kidney structure remains intact. Antibacterial agent 376 causes a significant decrease in serum antioxidant markers GSH, GPx, and CAT, indicating the induction of oxidative stress in rats. Antibacterial agent 376 can be used for research on bacterial infections (Staphylococcus aureus and Escherichia coli).
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- Fòrmula: C45H51Cl3N6
- Peso molecular:782.29
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Descripciòn
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar (Adult male, 180-220 g)[1]
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Dosage:0.03 g/kg
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Administration:i.p.; single administration
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Result:Reduced serum GSH to 42.9 ng/L, GPx to 3.20 ng/mL, and CAT to 77.95 ng/L.
Induced slight hepatic histopathological changes including minimal inflammatory cell infiltration, moderate vacuolar degeneration, and moderate hepatocellular enlargement.
Induced moderate renal changes including reduced inflammatory cell infiltration, mild vascular obstruction, and moderate tubular degeneration.
Chemical Information
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Peso molecular 782.29
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Fòrmula C45H51Cl3N6
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SMILES
C1(CCC[N+]2=CN(CC3=CC=CC=C3)C=C2)=CC(CCC[N+]4=CN(CC5=CC=CC=C5)C=C4)=CC(CCC[N+]6=CN(CC7=CC=CC=C7)C=C6)=C1.[Cl-].[Cl-].[Cl-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 376 Related Classifications
HY-189412 Related Classifications
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