1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Anticancer agent 49

Anticancer agent 49 

Cat. No.: HY-146358
Handling Instructions

Anticancer agent 49 (compound 69) is a broad spectrum anticancer agent. Anticancer agent 49 inhibits tubulin polymerization. Anticancer agent 49 shows antiproliferative activity. Anticancer agent 49 has the potential for the research of solid and hematological tumors.

For research use only. We do not sell to patients.

Anticancer agent 49 Chemical Structure

Anticancer agent 49 Chemical Structure

CAS No. : 2395009-34-2

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Description

Anticancer agent 49 (compound 69) is a broad spectrum anticancer agent. Anticancer agent 49 inhibits tubulin polymerization. Anticancer agent 49 shows antiproliferative activity. Anticancer agent 49 has the potential for the research of solid and hematological tumors[1].

In Vitro

Anticancer agent 49 (compound 69) inhibits tubulin polymerization and MCF-7 cancer cell growth with IC50s of 0.38 µM and 15 nM, respectively[1].
Anticancer agent 49 shows antiproliferative activity with IC50s of 5, 8, 10, 10, 12 nM for KU812, LAMA84-S, LAMA84-R, KBM5-WT, KBM5-T315I cells, respectively[1].
Anticancer agent 49 shows growth inhibition with IC50s of 22, 48, 24, 303, 147, 41, 34, 153, 61, 58 nM for U343G, U87MG, T98G, SK-N-BE, SK-N-BE(2)-C, HT29, HCT116, SW480, SW620, T24 cell, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

443.49

Formula

C26H25N3O4

CAS No.
SMILES

COC1=CC(C(C2=CN(C=C2C3=CC=C(C=C3)N)C4=CC=C(C=C4)N)=O)=CC(OC)=C1OC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Anticancer agent 49
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