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Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity.

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Anticonvulsant agent 2 Chemical Structure

Anticonvulsant agent 2 Chemical Structure

CAS No. : 75220-84-7

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Based on 1 publication(s) in Google Scholar

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Description

Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1].

In Vivo

Anticonvulsant agent 2 (compound10 a; 50 mg/kg, p.o.) decreases locomotor activity with an inhibition rate of 21.01% in rat[1].
Anticonvulsant agent 2 (50 mg/kg; p.o.) shows antiepileptic activity with an inhibition rate of 24.45% in rat[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 180-250g, male Wistar rats[1]
Dosage: 50 mg/kg
Administration: P.o.
Result: Showed antiepileptic activity with the inhibition rate of 24.45%.
Molecular Weight

332.83

Formula

C21H17ClN2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

ClC1=CC=C(C2=NC3=CC=CC=C3NC(C4=CC=CC=C4)C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (375.57 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0045 mL 15.0227 mL 30.0454 mL
5 mM 0.6009 mL 3.0045 mL 6.0091 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0045 mL 15.0227 mL 30.0454 mL 75.1134 mL
5 mM 0.6009 mL 3.0045 mL 6.0091 mL 15.0227 mL
10 mM 0.3005 mL 1.5023 mL 3.0045 mL 7.5113 mL
15 mM 0.2003 mL 1.0015 mL 2.0030 mL 5.0076 mL
20 mM 0.1502 mL 0.7511 mL 1.5023 mL 3.7557 mL
25 mM 0.1202 mL 0.6009 mL 1.2018 mL 3.0045 mL
30 mM 0.1002 mL 0.5008 mL 1.0015 mL 2.5038 mL
40 mM 0.0751 mL 0.3756 mL 0.7511 mL 1.8778 mL
50 mM 0.0601 mL 0.3005 mL 0.6009 mL 1.5023 mL
60 mM 0.0501 mL 0.2504 mL 0.5008 mL 1.2519 mL
80 mM 0.0376 mL 0.1878 mL 0.3756 mL 0.9389 mL
100 mM 0.0300 mL 0.1502 mL 0.3005 mL 0.7511 mL
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Anticonvulsant agent 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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