Antifungal agent 183

Antifungal agent 183 (compound B33) (10 mg/L) exhibits potent antifungal activity against Botrytis cinerea, with a growth inhibition rate of 84.82%^[2].
Antifungal agent 183 (0.5-8 mg/L) exhibits dose-dependent antifungal activity against Botrytis cinerea, with an EC₅₀ of 2.8231 mg/L and an EC₉₀ of 47.7223 mg/L^[2].
Antifungal agent 183 (5 μmol/L; 30 min; 40 min; 40 min) effectively inhibits the ATPase activity of BcMyoI, with an inhibition rate of 84.67% at 5 μM^[1].
Antifungal agent 183 (5 min) binds tightly to BcMyoI with a K_d of 0.37 μM^[1].
Antifungal agent 183 (500 ns) stably binds to the conserved phenamacril-binding pocket of BcMyoI with a binding free energy of −30.29 kcal/mol^[1].
Antifungal agent 183 (1-10 mg/L; 3 days) exhibits potent concentration-dependent antifungal activity against B. cinerea, with an EC₅₀ of 2.82 mg/L^[1].
Antifungal agent 183 (2.82-47.72 mg/L; 5 days) severely disrupts normal hyphal tip morphogenesis in B. cinerea, causing extensive tip swelling and hyperbranching at higher concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .