country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-115725

Copy Link Print Information

Antileishmanial agent-1

Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC₅₀ = 15.52 μM) and intracellular amastigotes (IC₅₀ = 4.10 μM).

For research use only. We do not sell to patients.

CAS No.: 2454115-43-4
Formula: C₁₅H₁₁Br₂N₃O
Molecular Weight:409.08

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antileishmanial agent-1 Chemical Structure

CAS No.: 2454115-43-4

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC₅₀ = 15.52 μM) and intracellular amastigotes (IC₅₀ = 4.10 μM).

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Peritoneal macrophage	CC₅₀	84.01 μM Compound: 4	Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 34427442]

Chemical Information

CAS No. 2454115-43-4
Molecular Weight 409.08
Formula C₁₅H₁₁Br₂N₃O
SMILES

OC(C1=CC=C(Br)C=C1)C2=CN(C3=CC=C(Br)C=C3)N=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64(17):12691-12704. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Antileishmanial agent-1

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Antileishmanial agent-1 Related Classifications

HY-115725 Related Classifications