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United States

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Cat. No.: HY-168208

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Antimalarial agent 45

Antimalarial agent 45 (compound 8I) is a antimalarial agent and shows antiplasmodial activity the IC₅₀ of 0.21 μM. Antimalarial agent 45 can be used for study of malaria.

For research use only. We do not sell to patients.

Formula: C₃₃H₃₄N₄O₃
Molecular Weight:534.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Antimalarial agent 45 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Antimalarial agent 45 (compound 8I) is a antimalarial agent and shows antiplasmodial activity the IC₅₀ of 0.21 μM. Antimalarial agent 45 can be used for study of malaria^[1].

All Parasite Isoforms :

Chemical Information

Molecular Weight 534.65
Formula C₃₃H₃₄N₄O₃
SMILES

O=C(N1CCN(C2=NC(C3=CC=C(CC)C=C3)=CC(C4=CC=C(OC)C(OC)=C4)=N2)CC1)/C=C/C5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Francis Kayamba, et al.A promising class of Antiprotozoal agents, design and synthesis of novel Pyrimidine–Cinnamoyl Hybrids. European Journal of Medicinal Chemistry. Available online 8 October 2024, 116944.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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