Antiparasitic agent-18
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC50=0.4 μM), T. cruzi (EC50=0.21 μM), and L. donovani (EC50=0.26 μM). Antiparasitic agent-18 has potent antiprotozoal activity.
For research use only. We do not sell to patients.
- CAS No.: 2821884-59-5
- Formula: C25H21N7O
- Molecular Weight:435.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Parasite Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L929 | CC50 |
89.1 μM
Compound: 3a
|
Cytotoxicity against mouse L929 cells incubated for 72 hrs by fluorescence based microplate reader analysis
Cytotoxicity against mouse L929 cells incubated for 72 hrs by fluorescence based microplate reader analysis
|
[PMID: 37729094] |
| THP-1 | CC50 |
>50 μM
Compound: 3a
|
Cytotoxicity against human THP-1 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human THP-1 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 37729094] |
Chemical Information
-
CAS No. 2821884-59-5
-
Molecular Weight 435.48
-
Formula C25H21N7O
-
SMILES
O=C(NC1=CC=C(NC(C2=NC=CC=C2)=N)C=C1)C3=CC=C(NC(C4=NC=CC=C4)=N)C=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiparasitic agent-18 Related Classifications
HY-155281 Related Classifications
Powered by Bioz