Antiproliferative agent-22
Antiproliferative agent-22 (compound 2) is an anticancer agent. Antiproliferative agent-22 shoes anti-proliferative activities against MCF-7, MDA-MB-231 and MDA-MB-468 cells with IC50 values of 6.2 μM, 3.3 μM and 3.3 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1374305-45-9
- Formula: C17H13N3O3
- Molecular Weight:307.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
6.2 μM
Compound: 2
|
Antiproliferative activity against ER-positive human MCF7 cells after 24 hrs by MTT assay
Antiproliferative activity against ER-positive human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 22483392] |
| MDA-MB-231 | IC50 |
3.3 μM
Compound: 2
|
Antiproliferative activity against ER-negative human MDA-MB-231 cells after 24 hrs by MTT assay
Antiproliferative activity against ER-negative human MDA-MB-231 cells after 24 hrs by MTT assay
|
[PMID: 22483392] |
| MDA-MB-468 | IC50 |
3.3 μM
Compound: 2
|
Antiproliferative activity against ER-negative human MDA-MB-468 cells after 48 hrs by MTT assay
Antiproliferative activity against ER-negative human MDA-MB-468 cells after 48 hrs by MTT assay
|
[PMID: 22483392] |
Chemical Information
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CAS No. 1374305-45-9
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Molecular Weight 307.30
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Formula C17H13N3O3
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SMILES
O=C(C1=CC=NC=C1)N/N=C2C3=C(O)C=CC=C3C(C(C)=C/2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)