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Cat. No.: HY-152945

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Antiproliferative agent-22

Name: Antiproliferative agent-22
Brand: MedChemExpress
SKU: HY-152945
Price: 358.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Antiproliferative agent-22 (compound 2) is an anticancer agent. Antiproliferative agent-22 shoes anti-proliferative activities against MCF-7, MDA-MB-231 and MDA-MB-468 cells with IC₅₀ values of 6.2 μM, 3.3 μM and 3.3 μM, respectively.

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CAS No.: 1374305-45-9
Formule: C₁₇H₁₃N₃O₃
Masse moléculaire:307.30

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antiproliferative agent-22 Chemical Structure

CAS No.: 1374305-45-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform NF-κB :

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	6.2 μM Compound: 2	Antiproliferative activity against ER-positive human MCF7 cells after 24 hrs by MTT assay Antiproliferative activity against ER-positive human MCF7 cells after 24 hrs by MTT assay	[PMID: 22483392]
MDA-MB-231	IC₅₀	3.3 μM Compound: 2	Antiproliferative activity against ER-negative human MDA-MB-231 cells after 24 hrs by MTT assay Antiproliferative activity against ER-negative human MDA-MB-231 cells after 24 hrs by MTT assay	[PMID: 22483392]
MDA-MB-468	IC₅₀	3.3 μM Compound: 2	Antiproliferative activity against ER-negative human MDA-MB-468 cells after 48 hrs by MTT assay Antiproliferative activity against ER-negative human MDA-MB-468 cells after 48 hrs by MTT assay	[PMID: 22483392]

Chemical Information

CAS No. 1374305-45-9
Masse moléculaire 307.30
Formule C₁₇H₁₃N₃O₃
SMILES

O=C(C1=CC=NC=C1)N/N=C2C3=C(O)C=CC=C3C(C(C)=C/2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Prasad Dandawate, et al. Synthesis, characterization, molecular docking and cytotoxic activity of novel plumbagin hydrazones against breast cancer cells. Bioorg Med Chem Lett. 2012 May 1;22(9):3104-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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