Antiproliferative agent-75
Antiproliferative agent-75, Pyrrole (HY-Y0807) derivative, is an antiproliferative agent with an IC50 value of 0.06 μM against Myc-driven human B-cells. Antiproliferative agent-75 can be used for the development of pyrrole-based Myc inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 3102226-11-6
- Formula: C28H26N2O3
- Molecular Weight:438.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antiproliferative agent-75 (Compound M13) (0.06-10 μM; 72 h) potently inhibits Myc-driven proliferation of human P493-6 cells with an IC50 of 0.06 μM without significant general cellular toxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Human lymphoblastoid B-cell line P493-6 (Myc-driven growth model)
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Concentration:10 μM
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Incubation Time:72 h
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Result:Inhibited P493-6 cell growth by ≥80% at 10 μM.
Chemical Information
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CAS No. 3102226-11-6
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Molecular Weight 438.52
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Formula C28H26N2O3
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SMILES
COC([C@@H](N1C(C2=CC=CC=C2)=C(C3=CC=CC=C3)C(C(N)=O)=C1C)CC4=CC=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)