2. Anti-infection
  3. Parasite
  4. Antitrypanosomal agent 5

Antitrypanosomal agent 5 (Compound 25)is a selective anti-trypanosomal agent with IC50s of 1 nM and 483.3 µM against T. brucei cell growth and HEK293 cells growth , respectively.

For research use only. We do not sell to patients.

Antitrypanosomal agent 5 Chemical Structure

Antitrypanosomal agent 5 Chemical Structure

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Antitrypanosomal agent 5 Related Antibodies

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Description

Antitrypanosomal agent 5 (Compound 25)is a selective anti-trypanosomal agent with IC50s of 1 nM and 483.3 µM against T. brucei cell growth and HEK293 cells growth , respectively[1].

In Vitro

After dosing T. brucei cells with Antitrypanosomal agent 5 (Compound 25; 200-1000 nM) for 12 hours, Western blot analyses shows Antitrypanosomal agent 5 inhibits tubulin polymerization in T. brucei cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitrypanosomal agent 5 Related Antibodies

Western Blot Analysis

Cell Line: T. brucei cells[1]
Concentration: 200nM; 500 nM; 1000 nM
Incubation Time: 12 hours
Result: Polymerized tubulin in T. brucei cells was significantly decreased with the treatment of Antitrypanosomal agent 5 at 500 nM and 1000 nM.
Molecular Weight

570.66

Formula

C30H30N6O4S
SMILES

CN(S(=O)(CC1=CC=CC=C1)=O)C2=CC=C(C=C2OCC3=CC=C(C=C3)C(N)=N)NC(C4=CC=CC(C(N)=N)=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antitrypanosomal agent 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitrypanosomal agent 5Antitrypanosomal agent5Antitrypanosomal agent-5Parasiteanti-trypanosomalT. bruceiHEK293Inhibitorinhibitorinhibit

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HY-146071
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