AP219

Cat. No.: HY-129303: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

AP39 (Item No. 17100) is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion.

For research use only. We do not sell to patients.

AP219 Chemical Structure

CAS No. : 779282-36-9

Size	Price	Stock
Solvent
1 mg (115.33 mM * 20 μL in Methylene chloride)		Ask For Quote & Lead Time
Solvent
5 mg (115.33 mM * 100 μL in Methylene chloride)		Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Description

Molecular Weight

433.54

Formula

C₂₈H₃₄O₂P⁺

CAS No.

779282-36-9

Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(CCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 99.67%

Select Batch:

Data Sheet (265 KB) SDS (252 KB)

COA (245 KB) RP-HPLC (1080 KB) MS (830 KB)

Handling Instructions (2659 KB)

References

[1]. Szczesny, et al. AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro. Nitric Oxide 41, 120-130 (2014).

AP219 Related Classifications

Metabolic Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AP219779282-36-9AP 219AP-219Endogenous MetaboliteInhibitorinhibitorinhibit

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AP219

AP219 Related Antibodies

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AP219 Related Classifications

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