1. Neuronal Signaling Anti-infection
  2. Calcineurin Fungal
  3. APX879

APX879 is a fungal-specific calcineurin inhibitor that has less immunosuppressive activities and toxicities. APX879 is a C22-modified FK506 (HY-13756) analog, which maintains broad-spectrum antifungal activity.

For research use only. We do not sell to patients.

APX879 Chemical Structure

APX879 Chemical Structure

CAS No. : 1801372-27-9

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Description

APX879 is a fungal-specific calcineurin inhibitor that has less immunosuppressive activities and toxicities. APX879 is a C22-modified FK506 (HY-13756) analog, which maintains broad-spectrum antifungal activity[1][2].

Molecular Weight

860.08

Formula

C46H73N3O12

CAS No.
SMILES

CO[C@@H]1[C@]2([H])O[C@]([C@@H](C1)C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](C/C([C@@H](/C=C(C[C@@H](C[C@@H]2OC)C)\C)CC=C)=N/NC(C)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
APX879
Cat. No.:
HY-148992
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