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BPTES

63 Cited Publications
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Based on 63 publication(s) in Google Scholar

BPTES is an allosteric and selective glutaminase inhibitor with an IC50 of 0.16 μM.

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  • Reinheit: 98.04%
  • CAS. Nr.: 314045-39-1
  • Formel: C24H24N6O2S3
  • Molecular Weight:524.68
  • Speicherung:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • BPTES Chemical Structure
    BPTES Chemical Structure
  • Experimental Validation Results for BPTES
  • Experimental Validation Results for BPTES
  • Experimental Validation Results for BPTES
  • Experimental Validation Results for BPTES
  • Experimental Validation Results for BPTES
CAS. Nr.: 314045-39-1
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  • BPTES Chemical Structure
    BPTES Chemical Structure
    1/16
  • 1/16

    BPTES purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 May 15;16(1):4502. [Abstract]

    Customer Validation
     BPTES (3 μM, 3 days) had no effect on ACLY expression and H3K27 and H3K9 acetylation in patient CD4+ T cells.

  • 1/16

    BPTES purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 May 15;16(1):4502. [Abstract]

    Customer Validation
     BPTES (3 μM, 48 h) did not reverse the increase in IFNγ, T-bet, IL-17A, and RORγt expression in Tigit−/− CD4+ T cells cultured under Th1- or Th17-polarizing conditions.

  • 1/16

    BPTES purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 25:31:101608. [Abstract]

    Customer Validation
     BPTES (0-160μM, 24 h (left) and 48 h (right)) combined with RT (4Gy) inhibited cell growth in HepG2 cells.

  • 1/16

    BPTES purchased from MedChemExpress. Usage Cited in: Cell Metab. 2022 Nov 1;34(11):1843-1859.e11. [Abstract]

    Customer Validation
     BPTES treatment (3 μM, 55 min) reduced the maximal and spare respiratory capacity of Kcnj2f/f tumor-associated macrophages.

  • 1/16

    BPTES purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2020 Aug;85:106664. [Abstract]

    Customer Validation
     BPTES/CB839 could efficiently and specifically inhibit the NLRP1b inflammsome signaling pathway in J774A.1 cells. The cell lysate is analyzed by immunoblotting using anti-Caspase-1 and anti-GAPDH antibodies.

  • BPTES